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R. Sirtautiene, R. Bagdoniene; Retinopathy of Prematurity Is Supposed to Start in utero. Our Presumption . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4132.
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© ARVO (1962-2015); The Authors (2016-present)
To study pecularities of retina in a premature infant born in 31 weeks of gestation.
Pathohistological examination of two eyes of autopsied premature infant (GA–31 weeks, BW–1600 grams, survival –26 hours).
There were two active zones in the nerve fibre layer of the temporal retina. In the thickened anterior –a vanguard– retina there was present proliferation of primitive spindle shaped cells. In the rearguard zone there were primitive endothelial cells.
Pathohistological changes tantamount to stage 1 of retinopathy of prematurity (ROP) in temporal retina were observed 26 hours after the birth of the premature infant.
We speculate that the development of ROP is determined not only by postnatal but also by certain antenatal factors.
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