Abstract:
To develop a high fidelity (100 µm linear voxeldimension), artifact–free, 3 dimensional model of theeye. High resolution MRI of a fresh, isolated babooneye was performed using a custom receiver coil placed in a 2T, 45 cm MRI magnet. MRI images were artificially colorizedbased on tissue dielectric constant using Photoshop ver. 7.0(Adobe Systems, Inc.). Images were assembled into a 3 dimensionalmodel and manipulated using IDL ver. 6.1 (Research Systems,Inc.). High resolution MRI allowed construction of anaccurate 3 dimensional model of the baboon eye with voxel volumeof approximately 106 µm3. This represents an improvementin volumetric resolution over typical clinical MRI scans bya factor of 103. High resolution MRI of a fresh,isolated eye allowed construction of a high fidelity volumetricmodel useful for FDTD modeling and anatomic teaching. This projectwas performed under NHRC–DET Work Unit: 60284.
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • computational modeling • anatomy