Purchase this article with an account.
R.E. Rosenbaum, P.M. T. Garcia, J.P. S. Garcia, R.B. Rosen; A Comparison of Leakage by FA With Retinal Thickness Using Talia's Anatomy Imager in Patients With Diabetic Retinopathy . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4294.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
Purpose: To determine if a correlation exists between thickening observed using the RTA Anatomy Imager and leakage seen via fluorescein angiography in patients with clinically significant macula edema. Methods: A retrospective review was made of 20 patients with a clinical diagnosis of CSME who were examined with both RTA (Retinal Thickness Analyzer, Talia Visionary Diagnostics, Israel) and FA (Topcon, Japan). The RTA's 2D and 3D topographical thickness maps were overlaid on the corresponding FAs using Talia’s internal software . These images were then viewed with Talia’s voxel based AI program, which is capable of presenting RTA slits as 3D 3x3mm images superimposed on FAs that can be cut through both horizontally and vertically; with this option it is possible to visually correlate FA leakage in patients with CSME to the RTA’s measured thickness maps of these patients. Results: A variable correlation was found between the thickness seen on RTA and the leakage observed via FA. We found that this correlation was greater in patients whose RTA studies were not confounded by cataracts and other media disturbances. Conclusions:The RTA Anatomy Imager has the unique capability of analyzing 3–dimensional retinal thickness maps in conjuction with fluorescein angiography studies. At present it is unclear whether the variable correlation between thickness and leakage is due to measurement flaws of the RTA or signifies the variable correlation that is expected between leakage and thickening in general.
This PDF is available to Subscribers Only