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S. Shah, D. Sarraf; Optical Coherence Tomography Imaging of Metastatic Breast Carcinoma to the Macula Pre and Post Chemotherapy . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4310.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To describe the imaging characteristics by optical coherence tomography (OCT) of a metastatic breast cancer lesion to the submacular region pre and post chemotherapy. Methods: The OCT, fundus photographic, and flourescein angiographic (FA) features of metastatic breast carcinoma to the submacular region are described. The patient subsequently underwent systemic chemotherapy with repeat imaging. The OCT features status post chemotherapy are described. Results: A creamy placoid submacular lesion was identified that demonstrated early fluorescence with late staining by FA analysis. OCT imaging demonstrated a neurosensory detachment of the macula with a blocking effect of the underlying RPE and choroid. The patient received systemic chemotherapy with subsequent improvement of vision from 20/80 to 20/25, resolution of the neurosensory detachment and normalization of the macular anatomy by OCT analysis. Conclusions: This is the first case report describing the OCT imaging features of submacular metastatic breast carcinoma. This report illustrates the utility of OCT in identifying and evaluating a metastatic breast cancer lesion to the macula and in monitoring the response of the lesion to systemic chemotherapy.
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