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M. Kaido, R. Ishida, E. Goto, M. Dogru, M. Yamada, C. Sotozono, S. Kinoshita, K. Tsubota; Functional Visual Acuity in Stevens–Johnson Syndrome (SJS) . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4474.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To investigate the relation of the dynamic time–wise changes of visual acuity (the functional visual acuity :FVA ), with tear functions and ocular surface vital staining scores in SJS patients Methods: Fifteen eyes of 11 patients (mean age:39.1±22.4 years) out of 50 eyes of 25 patients with Stevens–Johnson syndrome in whom functional visual acuity could be measured were recruited in this study. We used the Functional Visual Acuity Meter (Nidek, Japan) and examined the time wise change in the continuous visual acuity during a blink–free period of 30 seconds. Schirmer test I and ocular surface vital staining with fluorescein and Rose Bengal were also examined. The patients’ eyes were divided according to tear quantity into 2 groups as those with Schirmer value<10 mm (n=7 eyes) and those with Schirmer score ≥ 10mm( n=8 eyes).The differences of FVA and vital staining scores between the two groups were also studied. Results: The mean logmar visual acuity was –0.17. The baseline logmar FVA of –0.17continously decreased to –0.59, –0.77, and –0.89 at 10, 20 and 30 seconds, respectively. The mean Schirmer test value was 11.6±9.6 mm and vital staining was positive in all cases.The time wise decline in FVA in eyes with Schirmer test value< 10 mm was of relatively greater extent compared to eyes with Schirmer test ≥10mm (p=0.08).Eyes with Schirmer test value< 10 mm had significantly higher vital staining scores compared to eyes with Schirmer test ≥10mm. Conclusions: FVA measurement was an effective method of evaluating the dynamic changes in vision in SJS patients and seemed to show a close relation with the status of tear quantity and ocular surface vital staining.
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