May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Pattern Reversal ERG and VEP – Comparison of Stimulation by LED, Monitor and a Maxwellian–View System
Author Affiliations & Notes
  • B. Link
    Dept. Ophthalmology,
    University Erlangen–Nuremberg, Erlangen, Germany
  • S. Ruehl
    Dept. Ophthalmology,
    University Erlangen–Nuremberg, Erlangen, Germany
  • A. Peters
    Dept. of Medical Informatics, Biometry and Epidemiology,
    University Erlangen–Nuremberg, Erlangen, Germany
  • A. Juenemann
    Dept. Ophthalmology,
    University Erlangen–Nuremberg, Erlangen, Germany
  • F.K. Horn
    Dept. Ophthalmology,
    University Erlangen–Nuremberg, Erlangen, Germany
  • Footnotes
    Commercial Relationships  B. Link, None; S. Ruehl, None; A. Peters, None; A. Juenemann, None; F.K. Horn, None.
  • Footnotes
    Support  DFG (SFB 539)
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 4562. doi:
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    • Get Citation

      B. Link, S. Ruehl, A. Peters, A. Juenemann, F.K. Horn; Pattern Reversal ERG and VEP – Comparison of Stimulation by LED, Monitor and a Maxwellian–View System . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4562.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Abstract:
 

Pattern stimulation is widely used to detect innerretinaldysfunction. Our aim is to construct a multifocal pattern stimulationset which allows the application of cyclic summation. In thiswork we describe a new pattern stimulation technique with LEDareas and compare the results with conventional methods.

 

 

Three normal subjects (all female, age 28 to 35 years) weretested. ERG was derived using Jet electrodes which were partiallyfixed beneath the lower eyelid. VEP was derived by an activeelectrode on the scalp over the visual cortex.

 

Three different techniques were used to generate a checkerboardpattern reversal stimulus: 1) 70Hz monitor, 2) a Maxwellian–viewsystem (MVS) equipped with a Xenon–arc lamp and a mechanicalmirror system and 3) a LED field (Roland Consult) consistingof 100 white LEDs. Check size was always 0,35per/°, fieldsize 12,8°, contrast > 98%. Two intensities (125 and340cd/m²) and four pattern reversal frequencies (4, 8,12 and 24 RPS) were studied. For each stimulus condition, 400sweeps were averaged. All tests were repeated on 4 days.

 

 

The following tables show the maximal amplitude of ERG afteraveraging all comparable measurements of all subjects:

 

 

  At 340cd/m² a similar distribution was observed.

 

Retinal stimulation with checkerboard pattern reversalis possible with LED and leads to comparable but slightly loweramplitudes respective to monitor and Maxwellian–view system.A prototype including 13 diode arrays for pattern reversal usingthe cyclic summation technique will be performed.

 

 
Keywords: electrophysiology: clinical 
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