May 2005
Volume 46, Issue 13
ARVO Annual Meeting Abstract  |   May 2005
Eye Growth Changes in Myopic Singapore Children
Author Affiliations & Notes
  • S.–M. Saw
    Community Occup & Family Med, National Univ Singapore MD3, Singapore, Singapore
    Singapore Eye Research Institute, Singapore, Singapore
  • W.–H. Chua
    Singapore Eye Research Institute, Singapore, Singapore
  • G. Gazzard
    Ophthalmology, Institute of Ophthalmology, London, United Kingdom
  • D.T. H. Tan
    Singapore Eye Research Institute, Singapore, Singapore
  • R.A. Stone
    Ophthalmology, University of Pennsylvania, Philadephia, PA
  • Footnotes
    Commercial Relationships  S. Saw, None; W. Chua, None; G. Gazzard, None; D.T.H. Tan, None; R.A. Stone, None.
  • Footnotes
    Support  National Medical Research Council (NMRC), NMRC/0695/2002, Singapore
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 4624. doi:
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    • Get Citation

      S.–M. Saw, W.–H. Chua, G. Gazzard, D.T. H. Tan, R.A. Stone; Eye Growth Changes in Myopic Singapore Children . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4624.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract: : Purpose: To assess the changes in biometry and refraction in young children aged 7 to 9 years followed prospectively in Singapore. Methods: Children in Grades 1 to 3 aged 7 to 9 years in 3 Singapore schools were invited to participate in the SCORM (Singapore Cohort study Of the Risk factors for Myopia) study. Yearly eye examinations in the school included cycloplegic refraction and biometry measures. Only myopic children (N=543) with 3–year follow–up data were included in this analysis. Results: The progression of myopia was fastest in the first year (mean=–0.88 D per year) and slowest in the third year (mean = –0.48 D per year) (p< 0.001). The 3–year cumulative myopia progression rate was – 2.03 D. Children who were younger, Chinese, female, and whose fathers had completed higher levels of education had significantly faster rates of progression of myopia, even after adjusting for these factors, school, reading in books per week and parental myopia. The 3–year changes in axial length, anterior chamber depth, lens thickness, vitreous chamber depth and corneal curvature were 0.89mm, –0.02mm, –0.01mm, 0.92mm and 0.01mm, respectively. Children with faster rates of progression of myopia had greater increases in axial length and vitreous chamber depth. Conclusions: The 3–year cumulative myopia progression rates (–2.03 D) and 3–year axial length increases (0.89 mm) are high. Age, gender, race and father’s educational level are the most important predictors of myopia progression. The primary structural component that drives the rapid elongation of the eyeball is increase in vitreous chamber depth.

Keywords: clinical (human) or epidemiologic studies: outcomes/complications • myopia • refractive error development 

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