Abstract
Abstract: :
Purpose: The three–dimensional quantitative measurement of the optic disc has become an inevitable method in the evaluation of glaucoma patients. We used the new Heidelberg Retina Tomograph (HRT II) to investigate stereometric parameters of optic discs in a healthy population. Methods: Over a period of two years 300 volunteers of different age–groups were examined. A full medical history was taken, fast threshold perimetry, air–puff tonometry and laser scanning tomography with the HRT II on both eyes of each subject were performed by the same physician in one setting. Automated discriminant functions, regression analysis and the new "Vancouver algorithm" were tested on this population. Results: A total of 283 eyes of 283 volunteers fulfilled the inclusion criteria of this study. The average disc area was 2.16 ± 0.4 mm2, the specificity of discriminant algorithms was very high in this population (Moorfields 99.4%, FSM 97.1 %, RB 99.5%). Conclusions: The HRT II is a reliable tool to evaluate the topography of the optic disc. Despite the large interindividual variability of optic nerve head topography, the specificity of common automated classification procedures was very high in our population.
Keywords: optic disc • clinical (human) or epidemiologic studies: biostatistics/epidemiology methodology • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)