May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Delayed Intraocular Pressure Elevation After Pupillary Dilation in Exfoliation Syndrome
Author Affiliations & Notes
  • W. Shihadeh
    Ophthalmology/Glaucoma, New York Eye & Ear Infirmary, New York, NY
  • R. Ritch
    Ophthalmology/Glaucoma, New York Eye & Ear Infirmary, New York, NY
    New York Medical College, Valhalla, NY
  • B. Scharf
    Ophthalmology/Glaucoma, New York Eye & Ear Infirmary, New York, NY
  • J.M. Liebmann
    Ophthalmology/Glaucoma, Manhattan Eye, Ear & Throat Hospital, New York, NY
    New York University Medical Center, New York, NY
  • Footnotes
    Commercial Relationships  W. Shihadeh, None; R. Ritch, None; B. Scharf, None; J.M. Liebmann, None.
  • Footnotes
    Support  Glaucoma Research Institute, New York, NY
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 4835. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      W. Shihadeh, R. Ritch, B. Scharf, J.M. Liebmann; Delayed Intraocular Pressure Elevation After Pupillary Dilation in Exfoliation Syndrome . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4835.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose: To determine the effect of pupillary dilation on intraocular pressure (IOP) in normotensive patients with exfoliation syndrome (XFS). Methods: In this prospective study, 25 eyes of 19 Caucasian patients (9 male, 10 female) with XFS were enrolled. All eyes were untreated, unoperated, and normotensive with full fields. Pre–dilation IOPs were measured. IOPs and pupil sizes were checked after dilation with tropicamide 1% and phenylephrine 2.5% eye drops hourly for four consecutive hours. Pigment cell release in the anterior chamber was recorded and labeled as: 1) None, 2) trace: < 5 pigment particles/ HPF, 3) +1 : 5–10 pigment particles/ HPF, 4) +2: 10–20 pigment particles/ HPF, 5) +3: 20–50 pigment particles/ HPF, and 6) +4: >50 pigment particles/ HPF. Results: Twelve eyes (48%) exhibited a rise in IOP ≥ 4 mmHg above the pre–dilation baseline IOP. Four eyes (16%) exhibited a rise ≥ 9 mmHg (range 9–28 mmHg). Post–dilation gonioscopy confirmed the presence of an open anterior chamber angle in all eyes. The maximum IOP was reached in three hours post–dilation in three eyes and in two hours in the remaining eyes. The four eyes with marked IOP rise exhibited an elevation between 1–7 mmHg at one hour. The extent of dilation as well as the extent of anterior chamber pigment release did not seem to affect the magnitude of IOP rise. Conclusions: Patients with XFS are at increased risk for developing significant delayed post–dilation IOP rises. This is particularly important in patients with advanced cupping and / or severe visual field loss who may not be able to tolerate a marked elevation of IOP for even a short period of time. An early, mild rise in IOP at one hour may serve as a warning sign for a more severe, delayed response. Eyes with XFS should have their IOPs monitored after dilation.

Keywords: intraocular pressure • pupil 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×