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K.F. Damji, A. Arnarsson, F. Jonasson, H. Sasaki, K. Sasaki; Central Corneal Thickness (CCT) in Individuals With Pseudoexfoliation (PEX) in the Reykjavik Eye Study (RES) . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4864.
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Purpose: CCT is emerging as an important variable in the management of patients with or at risk for open–angle glaucoma. Very few studies, however, appear to have examined CCT in patients with or at risk for PEX. The purpose of this study is to determine if CCT of individuals with PEX is significantly different from individuals without PEX in a population based study of Caucasian individuals. Methods: Data from the RES (1996) was analyzed. CCT was measured with Scheimpflug photography. Individuals with corneal or intraocular surgery, as well as those where measurements could not be done, were excluded. Results: Of the 952 right eyes that met the eligibility criteria, there were 753 individuals with no slit lamp evidence of PEX with a dilated exam, 134 who were considered PEX suspects, and 65 with definite evidence of PEX (central disc and/or peripheral band on the lens capsule). The mean CCT (+/– SD) in each of these groups was 0.527 +/– 0.040, 0.529 +/– 0.036, and 0.533 +/– 0.032. After adjusting for age and sex, this difference was not statistically significant (p<0.4). Conclusions: Individuals with PEX in the RES have CCT values that are the same as individuals without PEX.
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