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P. Fagerholm, A. Dellby, L. Bäckman; Descemet and/or Bowman Location of Corneal Opacities – A New Corneal Dystrophy? . Invest. Ophthalmol. Vis. Sci. 2005;46(13):4917.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To describe a new type of inherited corneal changes Methods: A family of 4 generations consisting of 19 members underwent ophthalmological examination including visual acuity,refraction, IOP measurement, slit lamp, fundus and Orbscan examnination.The medical history and ongoing medication were recorded. Results: A woman in the third generation presented with small (0.05–0.2 mm in diameter), rounded,flat , grayish opacities. These were located only on the outer surface of Descemets membrane in the peripheral 1 mm of the cornea in the whole circumference. In the central part (9 mm in diameter)over the entire surface, the opacities were located strictly on the inner surface of Bowmans layer. There were no opacities in the stroma.One son presented with the same type of opacities , but only the peripheral deep type of opacities.There was no history of disease or medication associated with the affected patients nor was there any reduction of visual acuity or glare . Conclusions: We have not found this peculiar distribution of opacities described previously in the cornea.
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