Abstract
Abstract: :
Purpose: To report the clinical features of the unifocal choroiditis establishing evidences of presumed toxoplasmic etiology. Methods:Interventional study where 7 healthy young patients (among 20 and 30 years old), experienced acute unilateral visual loss secondary to unifocal choroiditis. Clinical features, natural course, and follow–up were established. Results:All patients exhibited a solitary, elevated, yellow–white active focus of choroiditis with overlying subretinal fluid and in some cases subretinal hemorrhage. The lesions measured approximately 1 disc diameter size, with none or mild vitreous inflamation. Vision loss was related to the location of the lesion or the subretinal fluid with respect to the fovea. The patients with prolonged follow–up, elevated white plaque lesions persisted overtime. One out of 7 patients presented previous history of uveitis or corioretinal inactive scars. All of them presented the serum IgG positive for toxoplasmosis. All other systemic evaluations were unremarkable. Two patients were submitted to intravitreal tap, where protein chain reaction (PCR) for diferent etiologies were being analized. Conclusions: To our knowledge, this is the first report of a series of patients with diagnostic of Unifocal Solitary Choroiditis, where all of them presented laboratory evidence of previous toxoplasmic infection.
Keywords: choroid • toxoplasmosis • uveitis-clinical/animal model