May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Measuring Macular Thickness by OCT for Objective Assessment of Inflammatory Activity in Eyes With Uveitis
Author Affiliations & Notes
  • L. Akduman
    Saint Louis University Eye Inst, Saint Louis, MO
  • K. Khauv
    Saint Louis University Eye Inst, Saint Louis, MO
  • O. Yalcinbayir
    Saint Louis University Eye Inst, Saint Louis, MO
  • Footnotes
    Commercial Relationships  L. Akduman, None; K. Khauv, None; O. Yalcinbayir, None.
  • Footnotes
    Support  Unrestricted Departmental Grant from RPB
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 5111. doi:
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      L. Akduman, K. Khauv, O. Yalcinbayir; Measuring Macular Thickness by OCT for Objective Assessment of Inflammatory Activity in Eyes With Uveitis . Invest. Ophthalmol. Vis. Sci. 2005;46(13):5111.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To determine if macular thickness measured by OCT can be used as an objective measure of inflammatory activity in eyes with uveitis. Methods: We retrospectively reviewed the charts of 9 patients (16 eyes) with various forms of uveitis. Best–corrected visual acuity (BCVA), cell and flare scores on each visit, and average macular thickness measured by OCT when available were noted. Relationships between BCVA, macular thickness, cell and flare scores separately, and the inflammation index (cell+flare score) were analyzed. Results: Changes in the cell or flare scores alone did not correlate with BCVA or macular edema. Changes in the macular thickness measured by OCT correlated with BCVA (Pearson correlation coefficient=–0.64) and inflammation index (Pearson correlation coefficient=0.58). Conclusions: Macular thickness measured by OCT can be used to assess the inflammatory activity more objectively than clinically assessed cell or flare scores.

Keywords: uveitis-clinical/animal model • imaging/image analysis: clinical • macula/fovea 
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