May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Corneal Endothelium Perfluocarbon Citotoxicity After Injection of Perfluo–N–Octane in Micropigs Eyes
R.A. Bueno–Garcia; M. Parrochia; P. Covarrubias; G. Papa Oliva; H. Quiroz–Mercado; R. Naranjo Tackman; L. Estrada; A. Rodríguez– Reyes; S. Corredor
Author Affiliations & Notes
  • R.A. Bueno–Garcia
    Retina, APEC, Mexico, Mexico
  • M. Parrochia
    Retina, APEC, Mexico, Mexico
  • P. Covarrubias
    Retina, APEC, Mexico, Mexico
  • G. Papa Oliva
    Retina, APEC, Mexico, Mexico
  • H. Quiroz–Mercado
    Retina, APEC, Mexico, Mexico
  • R. Naranjo Tackman
    Retina, APEC, Mexico, Mexico
  • L. Estrada
    Retina, APEC, Mexico, Mexico
  • A. Rodríguez– Reyes
    Retina, APEC, Mexico, Mexico
  • S. Corredor
    Retina, APEC, Mexico, Mexico
  • Footnotes
    Commercial Relationships  R.A. Bueno–Garcia, None; M. Parrochia, None; P. Covarrubias, None; G. Papa Oliva, None; H. Quiroz–Mercado, None; R. Naranjo Tackman, None; L. Estrada, None; A. Rodríguez– Reyes, None; S. Corredor, None.
  • Footnotes
    Support  Fundacion Rio Arronte
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 5324. doi:
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      R.A. Bueno–Garcia, M. Parrochia, P. Covarrubias, G. Papa Oliva, H. Quiroz–Mercado, R. Naranjo Tackman, L. Estrada, A. Rodríguez– Reyes, S. Corredor; Corneal Endothelium Perfluocarbon Citotoxicity After Injection of Perfluo–N–Octane in Micropigs Eyes . Invest. Ophthalmol. Vis. Sci. 2005;46(13):5324.

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Abstract

Abstract: : Purpose: To investigate the effect of injected anterior chamber perfluoro–n–octane on micropigs corneas Methods: 4 pigs, 2 cases, 2 controls.Topcon SP 2000 p specular biomicroscopy: thickness, endothelial count, endothelial morphism. Measure Results: Median endothelial count preinjection was 3956 cell/mm2 and at 1 month post injection was 3816 cell/mm2. Median IOP preinjection was 11.5 mmhg and at 1 month post injection was13 mmhg. Median corneal thickness preinjection was 543 um and at 1 month post injection was 573 um.Histopathology analysis reveals no changes in endothelial count and transparency between cases and controls Conclusions: We have not found pathological changes in pig’s cornea, before and after the injection of perfluoro–n–octane

Keywords: clinical laboratory testing • anterior chamber 
© 2005, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
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