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R.A. Bueno–Garcia, M. Parrochia, P. Covarrubias, G. Papa Oliva, H. Quiroz–Mercado, R. Naranjo Tackman, L. Estrada, A. Rodríguez– Reyes, S. Corredor; Corneal Endothelium Perfluocarbon Citotoxicity After Injection of Perfluo–N–Octane in Micropigs Eyes . Invest. Ophthalmol. Vis. Sci. 2005;46(13):5324.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To investigate the effect of injected anterior chamber perfluoro–n–octane on micropigs corneas Methods: 4 pigs, 2 cases, 2 controls.Topcon SP 2000 p specular biomicroscopy: thickness, endothelial count, endothelial morphism. Measure Results: Median endothelial count preinjection was 3956 cell/mm2 and at 1 month post injection was 3816 cell/mm2. Median IOP preinjection was 11.5 mmhg and at 1 month post injection was13 mmhg. Median corneal thickness preinjection was 543 um and at 1 month post injection was 573 um.Histopathology analysis reveals no changes in endothelial count and transparency between cases and controls Conclusions: We have not found pathological changes in pig’s cornea, before and after the injection of perfluoro–n–octane
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