May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Corneal Endothelium Perfluocarbon Citotoxicity After Injection of Perfluo–N–Octane in Micropigs Eyes
Author Affiliations & Notes
  • R.A. Bueno–Garcia
    Retina, APEC, Mexico, Mexico
  • M. Parrochia
    Retina, APEC, Mexico, Mexico
  • P. Covarrubias
    Retina, APEC, Mexico, Mexico
  • G. Papa Oliva
    Retina, APEC, Mexico, Mexico
  • H. Quiroz–Mercado
    Retina, APEC, Mexico, Mexico
  • R. Naranjo Tackman
    Retina, APEC, Mexico, Mexico
  • L. Estrada
    Retina, APEC, Mexico, Mexico
  • A. Rodríguez– Reyes
    Retina, APEC, Mexico, Mexico
  • S. Corredor
    Retina, APEC, Mexico, Mexico
  • Footnotes
    Commercial Relationships  R.A. Bueno–Garcia, None; M. Parrochia, None; P. Covarrubias, None; G. Papa Oliva, None; H. Quiroz–Mercado, None; R. Naranjo Tackman, None; L. Estrada, None; A. Rodríguez– Reyes, None; S. Corredor, None.
  • Footnotes
    Support  Fundacion Rio Arronte
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 5324. doi:
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      R.A. Bueno–Garcia, M. Parrochia, P. Covarrubias, G. Papa Oliva, H. Quiroz–Mercado, R. Naranjo Tackman, L. Estrada, A. Rodríguez– Reyes, S. Corredor; Corneal Endothelium Perfluocarbon Citotoxicity After Injection of Perfluo–N–Octane in Micropigs Eyes . Invest. Ophthalmol. Vis. Sci. 2005;46(13):5324.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To investigate the effect of injected anterior chamber perfluoro–n–octane on micropigs corneas Methods: 4 pigs, 2 cases, 2 controls.Topcon SP 2000 p specular biomicroscopy: thickness, endothelial count, endothelial morphism. Measure Results: Median endothelial count preinjection was 3956 cell/mm2 and at 1 month post injection was 3816 cell/mm2. Median IOP preinjection was 11.5 mmhg and at 1 month post injection was13 mmhg. Median corneal thickness preinjection was 543 um and at 1 month post injection was 573 um.Histopathology analysis reveals no changes in endothelial count and transparency between cases and controls Conclusions: We have not found pathological changes in pig’s cornea, before and after the injection of perfluoro–n–octane

Keywords: clinical laboratory testing • anterior chamber 
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