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Y. Shimoda, R. Hamano, S. Kishi; Comparative Study of Therapeutic Modalities for Pit–Macular Syndrome . Invest. Ophthalmol. Vis. Sci. 2005;46(13):5437.
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Purpose: To compare the therapeutic effects for pit–macular syndrome. Methods: Twelve eyes of 12 cases (6 male and 6 female) whose ages ranged from 17 to 73 years (average, 45.2) were included. We treated 8 eyes with vitrectomy and gas tamponade, 2 eyes with simple gas injection (one eye had previous photocoagulation) and 2 eyes with laser photocoagulation at the temporal margin of optic disc. These eyes were followed up for 6 to 101 months (average, 32.9). Pre– and postoperative retinal tomography was obtained by repeated optical coherence tomography (OCT). Results:All 8 eyes with vitrectomy and gas tamponade attained retinal reattachment after postoperative periods of 5 to 17 months (average, 10.3). One eye (17 yrs girl) with intravitreal gas (100% SF6) injection attained foveal reattachment but had a recurrence after 11 months. She got final reattachment after additional gas injection. All these 10 eyes achieved remarkable visual improvement. In cases with vitrectomy, repeated gas tamponade promoted retinal reattachment. In one photocoagulated eye treated with simple gas injection, foveal detachment gradually resolved for 42 months. In 2 eyes with laser photocoagulation, foveal retinal detachment and macular retinoschisis persisted with unchanged visual acuity.Conclusions: Vitrectomy with gas tamponade appeared to be the best therapeutic modality for pit–macular syndrome. Simple intravitreal gas injection may be effective. Laser photocoagulation to temporal margin of optic disc appeared not beneficial. It took about 1 year to obtain complete retinal reattachment after vitrectomy or simple gas injection.
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