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J.–H. Kim, Y.–J. Lee, S.–Y. Shin, S.–M. Kang, J.–M. Lee, J.–H. Hwang, M.–K. Ko; The Factors Related With Epithelial Healing of Cornea After Vitrectomy for Proliferative Diabetic Retinopathy . Invest. Ophthalmol. Vis. Sci. 2005;46(13):5444.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To evaluate the factors that contribute to protraction of epithelial damage after vitrectomy for proliferative diabetic retinopathy(PDR) Methods:We retrospectively studied factors that may relate to protraction of epithelial damage and recovery time after epithelial damage in 76 eyes of 66 patients who underwent vitrectomy for PDR between August 2003 and August 2004. The 76 eyes in this study were divided into 2 groups: 17 eyes with epithelial damage persisting for more than 14 days (protracted group) and 59 eyes without epithelial damage or with disappearance of signs of epithelial damage in less than 13 days (non–protracted group) after vitrectomy. We compared the factors that may relate to protraction of epithelial damage and time to recovery from epithelial damage between the 2 groups. Results: The average recovery time from epithelial damage was 45.7±26.6 days in the protracted group and 2.6±2.4 days in the non–protracted group. The protracted group was statistically significant (P<0.05) in intraoperative epithelial debridement. BUN, insulin use, and epithelial defect during surgery was correlated with the time to recovery from epithelial damage (P<0.05) Conclusions: These results show that protracted recovery from epithelial damage after vitrectomy for PDR is correlated with impaired renal function, the methods of medical treatment, and epithelial debridement suggesting that particular attention should be paid to corneal epithelial damage in patients with these factors.
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