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P.–V. Jacomet, E. Lala–Gitteau, S. Arsene, P.–J. Pisella; Intraocular Foreign Bodies: Multivariate Analysis of Prognostic Factors in 58 Cases . Invest. Ophthalmol. Vis. Sci. 2005;46(13):5448.
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Purpose: To describe outcome in patients with intraocular foreign body (IOFB), documenting initial clinical characteristics and surgical management, in attempt to analyze visual prognostic factors and to classify them according to their importance. Methods: It is a retrospective interventional study of 58 consecutive patients, undergoing surgical removal of IOFB. A multivariate analysis, using a stepwise logistic regression model, allowed determining the influence of clinical and surgical independent variables studied on the best corrected final Visual Acuity (fVA). Results: fVA > 5/10 was obtained in 41 patients (71%) and > 1/10 in 51 patients (88%). The initial visual acuity (iVA) was found to be statistically significant predictor of a fVA > 7/10 (Odd Ratio=6,37, p=0,016). Prognostic factor for a poor outcome (fVA < 1/10) included traumatic cataract (OR=63,42, p=0,104), foreign body’s size (OR=1,454, p=0,97) and delay of its removal (OR=1,108, p=0,012). However cataract is the only one prognostic factor of an improvement of the visual acuity during the evolution (OR=3,21, p=0,048). Conclusions: Thanks to microsurgical progresses and to efficiency of the prevention of endophthalmitis, final visual outcome was excellent in 71% of patients. The more the iVA is high, the more the chances to have an excellent fVA are important. But the more the size of the IOFB and the more the delay of the removal of this one increase, and the more the risk of a poor visual outcome is important. In fact, the anatomical and functional prognosis of IOFB remains difficult to establish at the early clinical examination.
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