May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Influence of Refractive State on Mesopic/Scotopic Pupil Diameter and Anisocoria
Author Affiliations & Notes
  • C. Sanchez–Ramos
    Optics – Univ Compleutense, Esc Univ de Optica, Madrid, Spain
  • I. Moral–Martinez
    Optics – Univ Compleutense, Esc Univ de Optica, Madrid, Spain
  • P. Ortiz–Calcerrada
    Optics – Univ Compleutense, Esc Univ de Optica, Madrid, Spain
  • C. Puell–Marín
    Optics – Univ Compleutense, Esc Univ de Optica, Madrid, Spain
  • M. Pérez–Carrasco
    Optics – Univ Compleutense, Esc Univ de Optica, Madrid, Spain
  • A. Langa–Moraga
    Optics – Univ Compleutense, Esc Univ de Optica, Madrid, Spain
  • Footnotes
    Commercial Relationships  C. Sanchez–Ramos, None; I. Moral–Martinez, None; P. Ortiz–Calcerrada, None; C. Puell–Marín, None; M. Pérez–Carrasco, None; A. Langa–Moraga, None.
  • Footnotes
    Support  Instituto Mapfre–Seguridad Vial
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 5592. doi:
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      C. Sanchez–Ramos, I. Moral–Martinez, P. Ortiz–Calcerrada, C. Puell–Marín, M. Pérez–Carrasco, A. Langa–Moraga; Influence of Refractive State on Mesopic/Scotopic Pupil Diameter and Anisocoria . Invest. Ophthalmol. Vis. Sci. 2005;46(13):5592.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To establish the effect of the refractive state of a subject on pupil diameter and anisocoria in mesopic and scotopic conditions. Methods:A prospective evaluation was performed of the pupil size and refractive state of 68 subjects aged 16 to 56 years (24.27±6.2 years) free of any eye pathology. Measurements were obtained using the infrared, binocular pupillometer P2000 (Procyon Instruments Ltd) after a 5 min period of adaptation to mesopic conditions (3cd/m2). Determinations were made at three luminance levels: 0.04 lux (scotopic), 0.4 lux (low mesopic) and 4 lux (high mesopic). For each measurement, 10 photographs of both pupils were automatically taken. Refractive errors were determined using the Nidek mod.700 autorefractometer. Subjects were classified according to their refractive state as: emmetropes (+0.50 D to –0.50 D), myopes (from –0.75 D) and hypermetropes (from +0.75 D). Results: Pupil diameters were: RE 6.81±0.7 mm, LE 6.74±0.7 mm in scotopic conditions; RE 5.56±0.9 mm, LE 5.48±0.8mm in low mesopic conditions; and RE 4.04±0.6 mm, LE 4.03±0.5 in high mesopic conditions. For each luminance change, a miosis approaching 20% was produced. No significant differences between the right and left eye were noted. Pupil diameter varied significantly according to the environmental luminance level. Refractive states were (in spherical equivalents): RE –1.35±2.3 D and LE –1.34±2.3 D. Corneal radii of curvature were: RE 7.73±0.4 mm (43.91±1.61 D) and LE 7.69±0.3 mm (43.85±1.80 D). The degree of anisocoria was 4.10% for the scotopic conditions, 5.02% for the low mesopic luminance level and 4.28% for the high mesopic conditions. No significant differences were detected at any luminance level among the pupil diameters and anisocorias of the myopes, emmetropes and hypermetropes. Neither were significant differences observed according to sex. Conclusions: The refractive state of a subject bears no significant relationship with pupil size or anisocoria measured under mesopic/scotopic luminance conditions.

Keywords: pupil • refraction • clinical (human) or epidemiologic studies: prevalence/incidence 
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