May 2005
Volume 46, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2005
Extraction of Topographical Information From Visual Evoked Potentials With Three Active Electrodes
Author Affiliations & Notes
  • B.A. E. Mazinani
    Ophthalmology,
    University of Aachen, Aachen, Germany
  • T. Waberski
    Neurology,
    University of Aachen, Aachen, Germany
  • P. Walter
    Ophthalmology,
    University of Aachen, Aachen, Germany
  • Footnotes
    Commercial Relationships  B.A.E. Mazinani, None; T. Waberski, None; P. Walter, None.
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science May 2005, Vol.46, 5686. doi:
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    • Get Citation

      B.A. E. Mazinani, T. Waberski, P. Walter; Extraction of Topographical Information From Visual Evoked Potentials With Three Active Electrodes . Invest. Ophthalmol. Vis. Sci. 2005;46(13):5686.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To introduce and validate a mathematical model to predict visual evoked potentials at any surface location on the head on the base of a set of three active electrodes. Methods: From 10 healthy subjects (25–38, mean 29 years) continuous VEPs were recorded via 96 channels. On the base of the recordings at the positions POz’, O1’ and O2’, a source dipole vector was calculated for each time point of the recordings and VEP responses were back projected for any of the 96 electrode positions. Differences between the calculated and the actually recorded responses were corrected using a third order polynomial and quantified by coefficients of variation (CV). Results: The CV of the mean difference between calculated and recorded responses of the ten subjects was 2,8 ± 1,2 %. Conclusions: The "Mini–Brainmapping" model promises a great amount of additional diagnostic information with minimal additional recording efforts as already optionally suggested in the ISCEV standards with good predictive precision affirmed by low coefficients of variation.

Keywords: electrophysiology: clinical • topography 
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