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R.P. Mills, R. Gurses–Ozden, T. Otani, J. Lipyanik, J. Harman, V.M. Patella, M. Johnstone; Comparison of Central Corneal Thickness Measurements by Ultrasound Pachymetry and Optical Coherence Tomography (OCT–3) . Invest. Ophthalmol. Vis. Sci. 2004;45(13):135.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To compare central corneal thickness (CCT) measurements obtained using ultrasound pachymetry and OCT–3. Methods: Subjects undergoing pachymetry in a glaucoma clinic were enrolled. Complete ophthalmic examinations were performed in all patients. CCT was measured using ultrasound pachymetry (DGH 550, Pachette 2, DGH Technology, Inc., Exton, PA) and a custom corneal scan protocol on the OCT–3 (Version 3.0, Carl Zeiss Meditec, Inc., Dublin, CA). OCT corneal scan protocol was created by combining fast testing strategy with the raster scan protocol. The mean of three OCT–3 measurements was compared with the mean of three ultrasound pachymetry measurements for each eye. Results: Fifty eyes of 50 subjects (43 glaucoma, 3 ocular hypertension, 1 glaucoma suspect, 3 normal) were enrolled. Mean age was 64.8 ± 15.2 (range 31–94). The mean CCT measurements were consistently greater with ultrasound pachymetry than with OCT–3 (544.2 ± 32.1 µm vs. 528.8 ± 30.4 µm, p<0.0001, paired t–test). OCT–3 CCT measurements were highly correlated with ultrasound pachymetry measurements (r2=0.97, p<0.0001). Conclusions: A new corneal scan protocol for OCT–3 provides a noninvasive way of measuring corneal thickness which correlates well with standard ultrasound pachymetry.
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