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C. Allouch, O. Touzeau, V. Borderie, R. Kopito, S. Boutboul, E. Zito, N. Rondeau, L. Laroche; Age related changes in ocular biometry . Invest. Ophthalmol. Vis. Sci. 2004;45(13):143.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To study the variation in biometric parameters obtained by Orbscan and A–scan ultrasound according to the patients' age. Methods: 200 normal eyes of 100 patients from 10 to 95 years old were prospectively studied. We analyzed the biometric measurement ( i.e.; pupil diameter, pachymetry, anterior chamber depth, irido–corneal angle measurements, lens thickness, axial length and corneal diameter) using Orbscan and A Scan–ultrasound. These parameters were correlated with the age of patients. Results: Age was correlated with different parameters: pupil diameter (r2 =–0.45, p<0.001), anterior chamber depth (r2= –0.74, p<0.001), lens thickness (r2= 0.78, p<0.001), irido–corneal angle measurement (r2 = –0.63, p<0.001) and pachymetry (r2=0.32, p<0.001). Corneal thickness increases to 6.7 µm for each decade of life and lens thickness increases to + 0.23 mm per decade, whereas anterior chamber depth decreases to 0.22 mm and irido–corneal angle decreases to 1.8° per decade. The axial length and corneal diameter were no correlated with age of the patients. Anterior chamber depth and irido–corneal angle were significantly correlated with lens thickness (r2= 0.51, p<0.001) Conclusions:The decrease in the anterior chamber depth and the closure of the irido–corneal angle measurement could be explained by the increase in lens thickness
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