Abstract
Abstract: :
Purpose:To evaluate and compare standard refractive outcomes, visual acuity, higher order aberrations (HOA), corneal sensitivity and contrast sensitivity in LASIK cases performed with the IntraLase® FS Laser and Bausch & Lomb® Hansatome® microkeratomes. Methods:A prospective study of 100 patients undergoing bilateral LASIK with each eye randomized to flap creation with INTRALASE® FS Laser or Hansatome® keratome. Refractive correction was performed with Alcon® CustomCornea® (50 patients) or LADARVision 4000 excimer laser (50 patients). Visual acuity, residual astigmatism, corneal sensitivity, HOA and contrast sensitivity was measured and compared for each keratome group up to 3 months postoperatively. Results: Uncorrected Visual Acuity:
Table 1: Uncorrected Visual Acuity (ETDRS) at Postoperative Visits Manifest Refraction: Both residual spherical equivalent (MRSE) and residual astigmatism at 1–month were nearly double in the Hansatome group vs. IntraLase group. The MRSE for IntraLase–treated eyes was –0.13 D +/– 0.28 vs. –0.29 D +/– 0.33 for Hansatome–treated eyes (p=0.001). HOA: Statistically significant increases in Spherical Aberration and X–axis Trefoil were seen in both IntraLase and Hansatome groups. The Hansatome group also showed statistically significant increases in Y–axis Coma and X–axis Quadrafoil. Corneal Sensitivity: At 1–week and 1–month postoperative visits, corneal sensitivity testing was performed including esthesiometer, Schirmer’s and corneal staining. All three tests indicated that IntraLase created flaps have greater retention of normal corneal sensitivity than Hansatome created flaps. Contrast Sensitivity: CST–1800 testing showed that IntraLase created flaps gained contrast sensitivity at every spatial frequency at 1–month postoperatively, which was greater than that with Hansatome created flaps. 50% of the test points were statistically significant at p<0.05. Conclusion:Statistically and clinically significant improvements in standard refractive outcomes, HOA, corneal and contrast sensitivity were noted between eyes in which Custom Cornea® LASIK was performed with the IntraLase® FS vs. Hansatome® keratome.
Keywords: refractive surgery • refractive surgery: other technologies • contrast sensitivity