May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Relationship Between Higher Order Aberrations and Pupil Size in Ametropic Eyes, before and after wavefront guided LASIK With the LADARWave System
Author Affiliations & Notes
  • E. Maguen
    Ophthalmic Clinical Trials Ctr, Cedars–Sinai Medical Center, Los Angeles, CA
  • S. Su
    Ophthalmic Clinical Trials Ctr, Cedars–Sinai Medical Center, Los Angeles, CA
  • J. Schlanger
    Ophthalmic Clinical Trials Ctr, Cedars–Sinai Medical Center, Los Angeles, CA
  • J.J. Salz
    Ophthalmic Clinical Trials Ctr, Cedars–Sinai Medical Center, Los Angeles, CA
  • Footnotes
    Commercial Relationships  E. Maguen, None; S. Su, None; J. Schlanger, None; J.J. Salz, Alcon C, R.
  • Footnotes
    Support  Discovery Fund For Eye Research
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 213. doi:
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      E. Maguen, S. Su, J. Schlanger, J.J. Salz; Relationship Between Higher Order Aberrations and Pupil Size in Ametropic Eyes, before and after wavefront guided LASIK With the LADARWave System . Invest. Ophthalmol. Vis. Sci. 2004;45(13):213.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To evaluate the relationship between pupil size and higher order aberrations as represented by the root mean square value (RMS) in eyes which underwent wavefront guided LASIK and to compare results before and after surgery. A linear relationship was demonstrated previously between pupil size and total aberrations as represented by the root mean square value (RMS). Methods: 27 eyes (14 patients) had diagnostic wavefront measurements with dilated pupils. Total aberrations, spherical aberration, and coma were recorded using RMS values preoperatively and three months postoperatively. Software integrated within the LADARWave system allowed simulation of all of the above aberrations for increments of 0.5mm of pupil size. The mean RMS±SD was calculated for each pupil diameter. The coefficient of determination R2 was determined by linear regression analysis. Results: A significant decrease in the coefficient of determination R2 was found when linear trend was evaluated between pupil diameter and higher order aberrations (total, spherical and coma) after surgery as follows:  

Conclusions: The less linear relationship between pupil size and higher order aberrations probably reflects an increase in irregularity of the corneal surface following LASIK. This method could be used as a simple means to assess the performance of a wavefront guided system for LASIK.

Keywords: refractive surgery: LASIK • pupil 
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