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P.A. Brannan, D. Hudak, R. Kersten, S. Schneider, K. Golnik, D. Kulwin; Sclerosing Idiopathic Orbital Inflammation: The first case with isolated optic nerve involvement . Invest. Ophthalmol. Vis. Sci. 2004;45(13):265.
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Purpose: To describe the first case of sclerosing idiopathic orbital inflammation involving only the optic nerve Methods: The clinical presentation, workup, and pathology of a case of sclerosing idiopathic orbital inflammation limited to the optic nerve are presented Results: The patient had an unexplained optic neuropathy with progressive visual loss. A complete laboratory evaluation and CT imaging of the orbit were normal. Fluorescein angiography showed central retinal artery and vein occlusions. MRI showed enhancement of a small section of nerve and biopsy confirmed the diagnosis of sclerosing idiopathic orbital inflammation involving only the optic nerve. Conclusions: : Sclerosing idiopathic orbital inflammation may affect the optic nerve resulting in visual loss in the absence of mass effect and must be considered in the differential diagnosis of unexplained optic neuropathy.
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