May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Efficacy of preoperative intravenous injection of antibiotic (Flomoxef sodium: FMOX) to reduce bacteria in conjunctiva and aqueous humor at theconclusion of cataract surgery.
Author Affiliations & Notes
  • Y. Kusano
    Dept. of Ophthalmology, St. Luke's International Hosp., Chuo–ku, Tokyo, Japan
  • S. Kogure
    Dept. of Ophthalmology, St. Luke's International Hosp., Chuo–ku, Tokyo, Japan
  • T. Yamaguchi
    Dept. of Ophthalmology, St. Luke's International Hosp., Chuo–ku, Tokyo, Japan
  • Footnotes
    Commercial Relationships  Y. Kusano, None; S. Kogure, None; T. Yamaguchi, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 289. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Y. Kusano, S. Kogure, T. Yamaguchi; Efficacy of preoperative intravenous injection of antibiotic (Flomoxef sodium: FMOX) to reduce bacteria in conjunctiva and aqueous humor at theconclusion of cataract surgery. . Invest. Ophthalmol. Vis. Sci. 2004;45(13):289.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose:In Japan, prophylactic intravenous injection of antibiotic before catacact surgery is still common. We sought to determine the efficacy of reducing conjunctival bacterial flora with intravenous injection of Flomoxef sodium (FMOX) which is one of the most commonly used antibiotic in Japan, before cataract surgery. Methods:Ninety–eight consecutive eyes of 98 patients having planned cataract surgery (phacoemulsification) with intraocular lens implantation were included in this study. In the study group, 39 eyes of 39 consecutive patients were given intravenous injection of FMOX (2.0g) one hour before cataract surgery. Fifty–nine eyes of 59 patients without preoperative FMOX injection were served as a control. All patients received topical sisomicin sulfate four times from one day before surgery and a 10% povidone–iodine scrub of the periorbital area before surgery. Conjunctival smears and aqueous humor fluid samples were obtained at the conclusion of surgery. These were sent to the microbiology laboratory for the culture. All samples were investigated for aerobe and anaerobe microorganisms. Results:Twenty–one percent (8/39) of eyes in the study group had positive conjunctival culture at the conclusion of surgery, compared with 22% (13/59) of eyes in the control group. Five percent (2/39) and 0 % (0/59) of eyes had positive culture from aqueous humor samples in the study group and control group, respectively. Pre–operative intravenous injection of FMOX was not effective in reducing bacteria in conjunctiva and aqueous humor at the conclusion of cataract surgery. None of the patient developed postoperative endophthalmitis in both groups. Conclusions: Preoperative intravenous injection of antibiotic (Flomoxef sodium) may not reduce bacteria in conjunctiva and aqueous humor at the conclusion of cataract surgery.

Keywords: clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials • antibiotics/antifungals/antiparasitics • cataract 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×