May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Preventive Effect Of Posterior Capusule Opacification Of Opti–Edge Design Intraocular Lens
Author Affiliations & Notes
  • Y. Katayama
    Dept Ophthalmology, Toho Univ Sch Med, Otaku, Japan
  • H. Yanagawa
    Dept Ophthalmology, Toho Univ Sch Med, Otaku, Japan
  • S. Kobayakawa
    Dept Ophthalmology, Toho Univ Sch Med, Otaku, Japan
  • Y. Katayama
    Dept Ophthalmology, Toho Univ Sch Med, Otaku, Japan
  • T. Tochikubo
    Dept Ophthalmology, Toho Univ Sch Med, Otaku, Japan
  • Footnotes
    Commercial Relationships  Y. Katayama, None; H. Yanagawa, None; S. Kobayakawa, None; Y. Katayama, None; T. Tochikubo, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 361. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Y. Katayama, H. Yanagawa, S. Kobayakawa, Y. Katayama, T. Tochikubo; Preventive Effect Of Posterior Capusule Opacification Of Opti–Edge Design Intraocular Lens . Invest. Ophthalmol. Vis. Sci. 2004;45(13):361.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose:Intraocular lens(IOL) with a sharp shaped optical edge has been found to be useful for prevention of posterior capsule opacification (PCO). However there is a problem of edgeglare. To improve this issue, the OptiEdge IOL, with a round–shaped front end and sharp–shaped back end, is marketed commercially. In this study, we compared preventive effects on PCO by a difference of edge configuration. Methods:Japanese white rabbits were implanted 3 kinds of silicone IOLs. Samples of optical edge are asfollows; SI40NB (AMO, Round–Edge group) with a round–shaped front and back end, AQ310NV(CANON STAAR, Sharp–Edge group) with a sharp–shaped front and back end, ClariFlex (AMO,Opti–Edge group)with a round–shaped front end and sharp–shaped back end. After phacoemulsification under general anesthesia , each type of IOLs were implanted.Each samples were enucleated at three weeks aftert surgery. PCO area were analyzed by Miyake–Apple view, and histopathologically observed the migration of lens epithelial cell(LEC), fibrous cell and capsule bag bending build–up. Results:The average value of PCO area was as follows; 48.2±8.5% for RE group (N=5), 20.2±9.0% for SE group (N=5), 18.8±9.6% for OE group (N=5). The value of RE group was significantly large compared with other groups, however the difference between SE and OE is not significantly large. The result shows that the number of samples, prevented the migration of LEC , is, 0 for RE group, 4 for SE group, 4 for OE group (in 5 samples). In both SE and OE group, capsule bags bending build–up on the back end are in good condition. These results couldn’t confirm the difference of LEC migration to posterior capsule side, which caused by the difference of front edge shape. Conclusions:As the result shows, compared with the round edge, the sharp edge and the opti–edge are effective for PCO prevention, and also have almost same preventive effect to this issue. The result suggests that the OptiEdge IOL would be desirable for clinical usage from optical point of view.

Keywords: cataract • posterior capsular opacification (PCO) 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×