May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Modified Transpupillary Thermotherapy (TTT) for submacular serous detachment in chronic serous choroidopathy (CSC)
Author Affiliations & Notes
  • F. Hamon
    Ophtalmologie, clinique ambroise pare – Centre Nord Vision, Lille, France
  • P. Salvetti
    Ophtalmologie, clinique ambroise pare – Centre Nord Vision, Lille, France
    Biomedical Physics, Schepens Eye Research Institute, Boston, MA
  • P. Goeminne
    Ophtalmologie, clinique ambroise pare – Centre Nord Vision, Lille, France
    Ophtalmologie, Université Catholique de Lille,, Lille, France
  • L. Cardoen
    Ophtalmologie, clinique ambroise pare – Centre Nord Vision, Lille, France
    Ophtalmologie, A Z Groeninge, Courtrai, Belgium
  • Footnotes
    Commercial Relationships  F. Hamon, None; P. Salvetti, None; P. Goeminne, None; L. Cardoen, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 531. doi:
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      F. Hamon, P. Salvetti, P. Goeminne, L. Cardoen; Modified Transpupillary Thermotherapy (TTT) for submacular serous detachment in chronic serous choroidopathy (CSC) . Invest. Ophthalmol. Vis. Sci. 2004;45(13):531.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose:To evaluate modified TTT as a possible treatment in the management of chronic CSC with subclinical or small serous retinal detachment. To try to improve functional prognosis. Methods:We have analyzed data from 5 eyes of 5 patients , between 38 and 74 years of age ( Mean 55 ) with chronic CSC between May 2002 and November 2003 treated by modified TTT. VA, fundus with evaluation of the macula, Scanning Laser Ophtalmoscopy (SLO) Heidelberg and Optical Coherence Tomography (OCT 3) examinations (pre–operative, after 6 weeks, and after several months) were performed. Mean follow–up period was 9 months (7–12 ). Preoperative visual acuity (VA) ranged from 20/200 to 20/70. All patients complained of visual disturbance, metamorphopsia and relative scotomas. Clinical symptoms had been present for at least 4 years an up to 10 years, VA being unchanged. Initial SLO showed macular retinal pigment epithelial abnormalities, atrophic changes and tracks. Pre–operative fluorescein angiography showed no acute recurrent CSC and no evidence of leakage. Pre–operative ICG revealed no active leakage points and no occult pigment epithelial detachments. OCT detected subclinical serous retinal detachment (< 100 µm high) or small (< 200 µm) for all patients. Results:Modified TTT (3 mm, 400 mW, 60 sec) was performed just after examination, which included OCT3, fluorescein and Indocyanine Green (ICG) angiographies. All patients had improvement of VA (mean 4 lines), reading capability improved and metamorphopsia decreased. OCT demonstrated resolution of exudation; normal foveal anatomy was demonstrated three months after treatment. No choroidal neovascularization (CNV) or complication was noted. Conclusions:This preliminary data seem to confirm the possibility to treat chronic CSC with TTT, often with surprising functional results. Stability of clinical situation for years before treatment makes it unlikely that natural history of the disease goes toward spontaneous resolution, showing that treatment seem to be efficient. SLO Heidelberg and OCT seems to be complementary in order to better understand this disease.

Keywords: macula/fovea • clinical (human) or epidemiologic studies: systems/equipment/techniques • retina 
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