Abstract
Abstract: :
Purpose: To describe clinical, histopathological findings as well as immunohistochemical profiles in patients with ocular lymphoma. Methods: Clinical pathological, retrospective, descriptive non comparative case series in biopsies of patients with diagnosis of ocular lymphoma from the Institute of Ophthalmology "Fundación Conde de Valenciana", Mexico City from 1991 to 2003, the biopsies were analyzed in the Department of Ocular Pathology Results: During the immunohistochemical analysis of 16 cases 4 were excluded because we found that those cases were not lymphoma. The final diagnosis was made with the histological features and immunohistochemical stains. The cases were classified in the REAL classification criteria; we found 41.66% marginal zone mucosa–associated lymphoid tissue (MALT); 25 % follicular ; 8.33% lymphoplasmocytic and 33.33% diffuse lymphoma. Most lymphomas were low grade 75% and their cellular type was B (CD20 +) in 91.66 %. Lymphoma was found 58.33 % in females. The age range was between 24 to 86 years, the average was 60 years. In the inicial period the incidence of lymphoma was between 0 to 1 per year, since 2001 the number of cases increased. Conclusions: The evaluation of patients with ocular lymphoma needs detailed clinical analysis, histopathological and immunohistochemical studies. We have to consider if there is an external or enviromental factor that affects the incidence of lymphoma.
Keywords: immunohistochemistry • clinical (human) or epidemiologic studies: prevalence/incidence • microscopy: light/fluorescence/immunohistochemistry