May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
The level of TGF–ß2, VEGF, and total protein in the aqueous humor in patients with Neovascular glaucoma and its relation to the surgical outcome of Ahmed valve implantation
Author Affiliations & Notes
  • C.Y. Kim
    Ophthalmology, Yonsei Univ Coll Med, Seoul, Republic of Korea
  • Y.J. Hong
    Ophthalmology, Yonsei Univ Coll Med, Seoul, Republic of Korea
  • G.J. Seong
    Ophthalmology, Yonsei Univ Coll Med, Seoul, Republic of Korea
  • W.K. Song
    Ophthalmology, Yonsei Univ Coll Med, Seoul, Republic of Korea
  • I.S. Kim
    Ophthalmology, Yonsei Univ Coll Med, Seoul, Republic of Korea
  • Footnotes
    Commercial Relationships  C.Y. Kim, None; Y.J. Hong, None; G.J. Seong, None; W.K. Song, None; I.S. Kim, None.
  • Footnotes
    Support  No
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 996. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      C.Y. Kim, Y.J. Hong, G.J. Seong, W.K. Song, I.S. Kim; The level of TGF–ß2, VEGF, and total protein in the aqueous humor in patients with Neovascular glaucoma and its relation to the surgical outcome of Ahmed valve implantation . Invest. Ophthalmol. Vis. Sci. 2004;45(13):996.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose: To assess the relationship between the level of TGF– ß2, VEGF, and total protein in the aqueous humor and the results of Ahmed valve implantation in patients with neovascular glaucoma (NVG). Methods: Nineteen eyes of 19 patients with Ahmed valve implantation due to neovascular glaucoma were studied. At the time of surgery, 0.1–0.2ml of aqueous humor was aspirated and stored at –70ºC until analysis. The level of TGF– ß2 and VEGF were measured by ELISA method, and total protein by Brandford method. Success was defined as IOP<21mmHg with or without anti–glaucoma medication. Results: The mean follow–up was 8.2 months ± 4.0(SD). The mean level of TGF– ß2, VEGF, and total protein in the aqueous humor were 5.4 ng/ml, 10.1ng/ml, and 94.4mg/dl, respectively. There was no difference in the level of TGF– ß2, VEGF, and total protein between success group and failure group (p>0.05). Using a Cox–regression analysis, the level TGF– ß2, VEGF, and total protein were not significant factors of surgical success. Conclusions: There was no significant relationship between the level of TGF– ß2, VEGF, and total protein in the aqueous humor and the results of Ahmed valve implantation in patients with NVG.

Keywords: growth factors/growth factor receptors • wound healing • anterior chamber 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×