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K. Wals; Side Effect Differences Between Intravitreal Injections of 4mg and 25mg Triamcinolone . Invest. Ophthalmol. Vis. Sci. 2004;45(13):1929.
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Purpose: To compare the side effects between intravitreal injections of 4 mg and 25 mg of triamcinolone Methods: Meta–analysis of clinical trials, case series, and case reports of intravitreal triamcinolone injections Results: Over 300 injection results were obtained. 48% of patients receiving intravitreal injections of 25 mg triamcinolone developed a significant elevation in intraocular pressure (>21 mm Hg), compared to 18% of those receiving 4 mg injections. 4% of patients receiving the 25 mg injections developed cataract, compared to 10% in those receiving 4 mg injections. Conclusions: Intravitreal injections of 25 mg triamcinolone were much more likely to cause a significant elevation in intraocular pressure compared to 4 mg injections. There was no significant difference in cataract progression between the two groups.
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