Triamcinolone Acetonide in the Anterior Chamber after Intravitreal Injection

Abstract

Abstract: : Purpose: To report the effects of triamcinolone acetonide (TA) in the anterior chamber. Methods: 250 patients were injected with triamcinolone acetonide via pars plana, 4 of them presented TA in the anterior chamber immediately after the procedure. This group was evaluated with specular microscopy and followed–up with best corrected visual acuity, intraocular pressure, complete ophthalmic evaluation and specular microscopy at 1 day, 15 days, 1,3 and 6 months after the injection. Results: Four patients with an age range from 54 to 77 years, 3 males and 1 female. Three patients were pseudophakic and one was phakic. Initial best visual acuity ranged from count–fingers to 20/80. All patients maintained corneal transparency during follow–up. Two patients presented increment of intraocular pressure (40–60 mmHg) and were treated successfully with paracentesis and topical beta–blockers. TA was observed in the anterior chamber during the first week after the procedure. Specular microscopy showed no change in endothelial cell count in any patient. Conclusions: Triamcinolone acetonide in the anterior chamber after intravitreal injection is a rare complication that may not be toxic to the cornea.

Keywords: retina • diabetic retinopathy • clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials