Abstract
Abstract: :
Purpose: To discuss the fundus fluorescein angiography (FA) and indocyanine green angiography (ICGA) features of patients with posterior uveal inflammation and to determine their values in different posterior uveal inflammatory disorders. Methods: Sixteen patients with inflammatory conditions of the posterior uvea were analyzed. All patients had comprehensive ophthalmologic examination, as well as colored and red–free fundus photography, and FA and ICGA. Results: Five cases were diagnosed with Vogt–Koyanagi–Harada disease. On FA, the peripheral retinal lesions were hyperfluorescent in early and late phases, whereas on ICGA they were hypofluorescent. Serpiginous choroiditis was diagnosed in 5 cases. The inactive lesions were hypofluorescent with hyperfluorescent borders on FA. The active lesions were hyperfluorescent in the early phases and were increasing in fluorescence throughout later phases. ICGA showed hypofluorescence of the inflamed lesions in all phases as well as choroidal vessel dilation and leakage in the vicinity of the active lesions. Two cases had birdshot chorioretinopathy. The lesions were hypofluorescent in the earlier phases with increasing hyperfluorescence throughout the late phases of FA. On ICGA the lesions were hypofluorescent. Multifocal choroiditis was the diagnosis in 4 cases. On FA the inactive lesions were hyperfluorescent in all phases due to RPE window defect. Active lesions increased in hyperfluorescence in the late phases. Hypofluorescence of both active and inactive lesions was observed in all phases ICGA. Conclusions: ICGA is a precious assistant to accurately assess the extent of the posterior ocular involvement in inflammatory disorders in deciding the degree of choroidal involvement. We suggest that ICGA should be performed together with FA in the diagnosis of the inflammatory diseases to estimate the magnitude of inflammation affecting the choroid and the retina.
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • uvea