Abstract
Abstract: :
Purpose:The OCT–3 volumetric and thickness analysis of macula in patients with acute anterior uveitis and to evaluate its possible role as a screening tool for macular oedema. Methods:Fifty consecutive patients with acute anterior uveitis in one eye with less than 1–week duration were involved in the study. All patients had serial scans using the fast macular thickness map protocol in the OCT–3 software. The scans were centred on the foveal fixation. Minimum foveal thickness (MFT), central 1 mm foveal thickness (CFT) and total macular volume (TFT, 3.45 mm and 6 mm) of both eyes were assessed.Patients with normal eye having vision less than 0.0 and having had anterior uveitis, intermediate uveitis or posterior uveitis in the previous 3 months were excluded from the study.Routinely all were assessed for visual acuity (Log MAR), severity of uveitis, and presence of clinically detectable macular oedema with Goldman contact lens fundus biomicroscopy.The difference in the foveal minimum and total macular volume between the two eyes were analysed using paired–samples T test (SPSS–10). Results:Three fourth of the patients had mild uveitis. None of them had detectable cystoid macular oedema on biomicroscopy. Mean MFT in affected eye (AE) was 183.41µ (SD= 47.22), and normal eye (NE) 178.32µ (SD= 40.36). The mean CFT (1mm) in the AE and NE were 214.6µ (SD=40.2) and 213.7µ (SD=37.7) respectively.The TMV (6 mm) in AE was 6.9mm3 (SD= 1) and NE was 7.0mm3 (SD= 0.6).There was no statistically significant difference in the minimum foveal thickness (p= 0.660), central 1 mm foveal thickness (p=0.903) or total macular volume (p= 0.305) noticed between the eye with uveitis and normal eye. Conclusions:Optical Coherence Tomography may not provide any additional information in acute anterior uveitis with clinically normal macula.
Keywords: uveitis–clinical/animal model • macula/fovea • imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)