May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Proptosis in Japanese patients with Dysthyroid Ophthalmopathy
Author Affiliations & Notes
  • A. Kozaki
    Ophthalmology, Olympia Eye Hosp, Tokyo, Japan
  • N. Komoto
    Ophthalmology, Olympia Eye Hosp, Tokyo, Japan
  • Y. Ishii
    Ophthalmology, Olympia Eye Hosp, Tokyo, Japan
  • T. Maeda
    Ophthalmology, Olympia Eye Hosp, Tokyo, Japan
  • Y. Inoue
    Ophthalmology, Olympia Eye Hosp, Tokyo, Japan
  • Footnotes
    Commercial Relationships  A. Kozaki, None; N. Komoto, None; Y. Ishii, None; T. Maeda, None; Y. Inoue, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 2717. doi:
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    • Get Citation

      A. Kozaki, N. Komoto, Y. Ishii, T. Maeda, Y. Inoue; Proptosis in Japanese patients with Dysthyroid Ophthalmopathy . Invest. Ophthalmol. Vis. Sci. 2004;45(13):2717.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To study how the severity of proptosis would influence patients' clinical characteristics in Japanese patients with dysthyroid ophthalmopathy. Methods: A total of 10,932 patients (21,863 eyes, 8,692 female, 2,240 male, mean age of 39.9 years ranging between 5 and 87) were evaluated for proptosis using a Hertel exophtalmometer,during the ten–year period between 1993 and 2002. MRI or CT scan analized enlargement of the extraocular muscle causing proptosis. The severity of eye changes was scored by the classification previously published by Inoue et al(Orbit.vol1.1982 ). Data were analyzed by multiple regression. Results: Teenagers showed severer proptosis which eventually decreased over time by age (p<.001). Men showed severer proptosis than women (p<.001). Enlargement of the extraocular muscle was observed more often in the older patients and also in men. The severity of eyelid fissure, eyelid swelling, diplopia and optic neuropathy showed positive correlation with the severity of proptosis. Female to male ratio was about four to one in all, but this ratio was one to one in 175 patients (1.6%) who showed proptosis more than 25mm. Conclusions: The degree of proptosis correlates well to the severity of ocular manifestations.

Keywords: orbit 
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