May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
A Newly Developed Peripheral Anterior Chamber Depth Analysis System– Principle, Accuracy, and Reproducibility–
Author Affiliations & Notes
  • K. Osada
    Ophthalmology, University of Yamanashi, Nakakoma–gun, Japan
  • K. Kashiwagi
    Ophthalmology, University of Yamanashi, Nakakoma–gun, Japan
  • F. Kashiwagi
    Kashiwagi Ophthalmic Clinic, Kofu, Japan
  • Y. Toda
    Ophthalmology, University of Yamanashi, Nakakoma–gun, Japan
  • T. Tsumura
    Ophthalmology, University of Yamanashi, Nakakoma–gun, Japan
  • S. Tsukahara
    Ophthalmology, University of Yamanashi, Nakakoma–gun, Japan
  • Footnotes
    Commercial Relationships  K. Osada, None; K. Kashiwagi, Kenji Kashiwagi P; Takagi Seiko Inc P; F. Kashiwagi, None; Y. Toda, None; T. Tsumura, None; S. Tsukahara, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 2778. doi:
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    • Get Citation

      K. Osada, K. Kashiwagi, F. Kashiwagi, Y. Toda, T. Tsumura, S. Tsukahara; A Newly Developed Peripheral Anterior Chamber Depth Analysis System– Principle, Accuracy, and Reproducibility– . Invest. Ophthalmol. Vis. Sci. 2004;45(13):2778.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To develop a new, non–contact system for measuring anterior chamber depth (ACD) quantitatively, and to investigate its accuracy as well as inter–observer and intra–observer reproducibility. Methods: The system scanned the ACD from the optical axis to the limbus in approximately 0.5 second and took 21 consecutive slit–lamp images at 0.4 mm intervals. A computer–installed program automatically evaluated the ACD, central corneal thickness (CT), and corneal radius of curvature (CRC) instantly. A dummy eye was used for investigating measurement accuracy. We examined the effects of CT and CRC on the measurement results using a computer–simulation model to minimize measurement errors. Three examiners measured the ACD in ten normal eyes, and inter– and intra–observer reproducibility was analyzed. Results: The ACD values measured by this system were very similar to theoretical values. Increase of CRC and decrease in CT decreased ACD and vise verse. Data calibration using evaluated CT and CRC successfully reduced measurement errors. Intra– and inter–observer variations were small. Their coefficient variation values were 7.4±2.3% and 6.7±0.7%, and these values tended to increase along the distance from the optical axis. Conclusion: The current system can measure ACD with high accuracy as well as high intra– and inter–observer reproducibility. It has potential use in measuring ACD quantitatively and screening subjects with narrow angle.

Keywords: anterior chamber • clinical laboratory testing • imaging/image analysis: clinical 
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