May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Autologous platelet rich plasma (PRP) as a biological adhesive in lamellar keratoplasty
Author Affiliations & Notes
  • F. Luengo
    Department of Ophthalmology,
    Hospital Universitario Austral and Facultad de Ciencias Biomedicas, Pilar, Buenos Aires, Argentina
  • J.I. Ferro
    Medical Transfusional Service,
    Hospital Universitario Austral and Facultad de Ciencias Biomedicas, Pilar, Buenos Aires, Argentina
  • S. Gatto
    Medical Transfusional Service,
    Hospital Universitario Austral and Facultad de Ciencias Biomedicas, Pilar, Buenos Aires, Argentina
  • S. Arias
    Medical Transfusional Service,
    Hospital Universitario Austral and Facultad de Ciencias Biomedicas, Pilar, Buenos Aires, Argentina
  • J.O. Croxatto
    Ocular Pathology, Fundacion Oftalmologica Argentina "Jorge Malbran", Buenos Aires, Argentina
  • J.E. Gallo
    Department of Ophthalmology,
    Hospital Universitario Austral and Facultad de Ciencias Biomedicas, Pilar, Buenos Aires, Argentina
  • Footnotes
    Commercial Relationships  F. Luengo, None; J.I. Ferro, None; S. Gatto, None; S. Arias, None; J.O. Croxatto, None; J.E. Gallo, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 2927. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      F. Luengo, J.I. Ferro, S. Gatto, S. Arias, J.O. Croxatto, J.E. Gallo; Autologous platelet rich plasma (PRP) as a biological adhesive in lamellar keratoplasty . Invest. Ophthalmol. Vis. Sci. 2004;45(13):2927.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose: To demonstrate the usefulness of autologous platelet rich plasma (PRP) as a biological adhesive in lamellar keratoplasty (LK) Methods: An autologous six millimeters lamellar graft was performed in 12 albino rabbits. Autologous PRP was applied on the stromal surface and the corneal botton was replaced. Topical tobramicine and dexametasone were postoperatively used. Rabbits were euthanised for histological evaluation at 48 hs, 1, 4, and 12 weeks after surgery. Results: Clinically, all the rabbits showed successful graft attachment and clear cornea at 12 weeks. Histopathologic examination showed mild inflammation in the initial stages and a well adhered lamellar graft with mild keratocyte activity at 12 weeks. Conclusions: Autologous platelet rich plasma may be a useful tool in lamellar keratoplasty and flap adherence after LASIK.

Keywords: cornea: stroma and keratocytes • cornea: basic science • transplantation 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×