May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Agreement of the Heidelberg Retina Tomograph II Macula Edema Module with Contact Lens Stereo Fundus Biomicroscopy in Early Diabetic Maculopathy.
M. Kisilevsky; C. Hudson; R.K. Nrusimhadevara; K. Guan; T. Wong; M. Mandelcorn; W.C. Lam; R.G. Devenyi; J.G. Flanagan
Author Affiliations & Notes
  • M. Kisilevsky
    Department of Ophthalmology and Vision Science, University of Toronto, Toronto, ON, Canada
    Multi–Disciplinary Laboratory for the Research of Sight–Threatening Diabetic Retinopathy, University of Waterloo, Waterloo, ON, Canada
  • C. Hudson
    Department of Ophthalmology and Vision Science, University of Toronto, Toronto, ON, Canada
    Multi–Disciplinary Laboratory for the Research of Sight–Threatening Diabetic Retinopathy, University of Waterloo, Waterloo, ON, Canada
  • R.K. Nrusimhadevara
    Department of Ophthalmology and Vision Science, University of Toronto, Toronto, ON, Canada
    Multi–Disciplinary Laboratory for the Research of Sight–Threatening Diabetic Retinopathy, University of Waterloo, Waterloo, ON, Canada
  • K. Guan
    Department of Ophthalmology and Vision Science, University of Toronto, Toronto, ON, Canada
  • T. Wong
    Department of Ophthalmology and Vision Science, University of Toronto, Toronto, ON, Canada
    Multi–Disciplinary Laboratory for the Research of Sight–Threatening Diabetic Retinopathy, University of Waterloo, Waterloo, ON, Canada
  • M. Mandelcorn
    Department of Ophthalmology and Vision Science, University of Toronto, Toronto, ON, Canada
  • W.C. Lam
    Department of Ophthalmology and Vision Science, University of Toronto, Toronto, ON, Canada
  • R.G. Devenyi
    Department of Ophthalmology and Vision Science, University of Toronto, Toronto, ON, Canada
  • J.G. Flanagan
    Department of Ophthalmology and Vision Science, University of Toronto, Toronto, ON, Canada
    Multi–Disciplinary Laboratory for the Research of Sight–Threatening Diabetic Retinopathy, University of Waterloo, Waterloo, ON, Canada
  • Footnotes
    Commercial Relationships  M. Kisilevsky, None; C. Hudson, None; R.K. Nrusimhadevara, None; K. Guan, None; T. Wong, None; M. Mandelcorn, None; W.C. Lam, None; R.G. Devenyi, None; J.G. Flanagan, None.
  • Footnotes
    Support  CIHR, PREA
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 2995. doi:
  • Views
  • Share
  • Tools
    • Alerts
      User Alerts
      You are adding an alert for:
      Agreement of the Heidelberg Retina Tomograph II Macula Edema Module with Contact Lens Stereo Fundus Biomicroscopy in Early Diabetic Maculopathy.
      You will receive an email whenever this article is corrected, updated, or cited in the literature. You can manage this and all other alerts in My Account
      The alert will be sent to:
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation
      Citation

      M. Kisilevsky, C. Hudson, R.K. Nrusimhadevara, K. Guan, T. Wong, M. Mandelcorn, W.C. Lam, R.G. Devenyi, J.G. Flanagan; Agreement of the Heidelberg Retina Tomograph II Macula Edema Module with Contact Lens Stereo Fundus Biomicroscopy in Early Diabetic Maculopathy. . Invest. Ophthalmol. Vis. Sci. 2004;45(13):2995.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

      ×
    • Get Permissions
  • Supplements
Abstract

Abstract: : Purpose: To determine the; (i). agreement of the Macular Edema Module (MEM) of the Heidelberg Retina Tomograph (HRT) II with contact lens stereo fundus biomicroscopy (FB) in patients with early diabetic maculopathy; and (ii). inter–relationship of MEM with the results of short–wavelength automated perimetry (SWAP) and fluorescein angiography (FA). Methods: The sample comprised 20 patients (mean age 59.15 years, SD 7.09) with mild–to–moderate diabetic retinopathy (DR). One eye of each patient was selected for the study; 11 eyes manifested diabetic macular edema (DME). Lenticular opacity that impacted on fundus visualization was an exclusion criterion. Using a dilated pupil, patients underwent MEM, FB, SWAP and FA. All outcome measures were assessed using a grid comprising 9 sectors centered on the fovea; the presence of abnormality was documented for each outcome measure in each grid sector. Results: Thirty seven of 180 sectors contained DME using FB. MEM demonstrated an abnormality identification rate (= TP / TP + FN) of 92% and a normality identification rate (= TN / FP + TN) of 85%. MEM showed good overall agreement (i.e. both techniques detected the same areas as normal or as abnormal) with SWAP (72 %) and FA (73 %). Virtually all areas of DME detected with MEM but not seen clinically had decreased sensitivity on SWAP and / or FA leakage. Conclusions:MEM demonstrated very good agreement with FB. Combining FA and SWAP with the MEM provided supporting evidence of blood–retinal barrier leakage and visual dysfunction in areas of early retinal edema. Prospective studies are on–going to fully assess the diagnostic test performance of MEM.

Keywords: imaging/image analysis: clinical • diabetic retinopathy • clinical (human) or epidemiologic studies: systems/equipment/techniques 
© 2004, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2025 Association for Research in Vision and Ophthalmology.
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.Accept