"OCT Valuation In Posterior Pole’s Retinoschisis"

Abstract

Abstract: : Purpose: Retinoschisis is characterized by cystic spaces that sometimes flow together in a large retinal splitting, similar to a cavity. Inherited as X–linked Juvenile Retinoschisis (XL–RS) is a rare bilateral vitreoretinal dystrophy usually cystic spaces are evident often star–shaped configuration around foveola. The object of our study is to evaluate through (OCT), 5 patients with XL–RS. Methods: We have examined 5 male patients 10 eyes (age range 20–25 years) with X–linked Juvenile Retinoschisis and progressive reduction of visual acuity. Mean BCVA was 20/50. Indirect ophthalmoscopy, slit–lamp biomicroscopy and fundus photography were performed in all patients every six months. From start to finish of 24 months we have studied the examined subjects with OCT and Electroretinography (ERG).Results: OCT’s images show a separation of neurosensorial retina that coincide with classical histopatology findings. Examination results were correlated with the dates of clinical examinations and compared with ERG’s dates too. OCT images underline an increase of retinal thickness with a separation into nerve fibre layer at foveal space. Instead OCT images about retinal detachment show a separation of whole neuroretinal layer on retinal pigmented epithelium (RPE).Cystic cavities were hypo–reflectant, laying for serous content.Conclusions: OCT images help us to evaluate retinal thickness increased and the presence of cystic cavities, with serous content, on nerve fibre layer of posterior pole. Therefore they could be an important finding in the progression of congenital retinoschisis.

Keywords: retinal degenerations: hereditary • clinical (human) or epidemiologic studies: systems/equipment/techniques • retinal degenerations: hereditary