May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Evaluation of test–retest variability for the preferential hyperacuity perimeter (PHP) in AMD patients
Author Affiliations & Notes
  • Y. Alster
    Ophthalmology, Notal Vision Inc, Tel Aviv, Israel
  • PHP research group
    Ophthalmology, Notal Vision Inc, Tel Aviv, Israel
  • Footnotes
    Commercial Relationships  Y. Alster, Notal Vision Ltd. E.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 3082. doi:
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      Y. Alster, PHP research group; Evaluation of test–retest variability for the preferential hyperacuity perimeter (PHP) in AMD patients . Invest. Ophthalmol. Vis. Sci. 2004;45(13):3082.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose:Visual field testing is known to have variability due to many variables such as VF defect severity, its location, pupil size. The PHP is a new macular perimeter for monitoring AMD. The aim of the study was to determine the test–retest variability of the PHP and to correlate between visual field abnormal findings and fluorescein angiography findings in patients with CNV Methods: Patients with intermediate AMD and patients with CNV secondary to AMD underwent 2 consecutive PHP exams 15 minutes apart. All intermediate patients underwent stereo color fundus photography and patients with CNV underwent fluorescein angiography to confirm diagnosis. Agreement between both tests and location correlation between the first test and FA were performed. All subject signed an informed consent Results: Forty–three patients with intermediate and 33 patients with CNV participated in the study. For the total study population the measure of agreement using Kappa statistics was 0.81. Of the 25 CNV patients who demonstrated abnormal visual field defect, the correlation between lesion location on the FA and VF was good in 16 patietns, moderate in 7 and poor in 2. Conclusions: The study demonstrated very good strength in agreement (Byrt 1996) between 2 consecutive PHP tests. It further demonstrated that in 92% abnormal findings do represent to a good or moderate degree the actual lesion location. This may further explain the good agreement between the two tests although it can only account for the positive CNV patients.

Keywords: age–related macular degeneration • visual fields • perimetry 
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