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D. Stanescu, S. Cohen, A. El Maftouhi; Predictive factors of successful single PDT session in subfoveal choroidal neovascularization . Invest. Ophthalmol. Vis. Sci. 2004;45(13):3149.
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Abstract: : Purpose:The purpose of this study was to evaluate the criteria of successful treatment by photodynamic therapy (PDT) in subfoveal choroidal neovascularization (CNV). Methods:Retrospective study of 548 patients who underwent PDT for subfoveal CNV in a tertiary reference retinal center between September 2001 and March 2003. Criteria of successful treatment were patients who received only one single PDT session and had an improvement of visual acuity of 2 lines or more on ETDRS charts. Age, sex, follow–up and CNV etiologies were recorded. Results:There were 548 patients who underwent PDT for subfoveal CNV. Twenty four patients received one single PDT session resulting in an improvement of 2 lines or more on ETDRS charts. Mean age was 67 years (range 54 to 88 years). There were 15 women and 9 men. Mean follow–up was 8.5 months. Twenty patients had subfoveal CNV secondary to myopia and the other four presented occult subfoveal choroidal neovascularization. None of the patients corresponding to successful criteria presented classic subfoveal CNV. Conclusions:Myopia and to a lesser extent occult choroidal neovascularization appear to be positve predictive factors of good response to photodynamic therapy
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