Abstract
Abstract: :
Purpose: To determine the rate of false negative results with the Heidelberg Retina Tomograph (HRT II) in a glaucoma practice. Design: Cross–sectional (Prevalence) study. Methods: We analysed the HRTs taken between October 2002 and October 2003 in our glaucoma clinic, and selected the patients who had a good quality image (SD < 40 µ) with a normal Moorfields Regression Analysis (MRA). A masked independent observer classified those patients as normal, glaucoma suspect, or glaucomatous on the basis of optic disc stereo photos (ODP) and at least 3 consecutive reliable automated perimetries. The diagnosis of glaucoma was based on a glaucomatous optic disc with a congruent, reproducible visual field defect. Results: Four hundred and fifty patients who had an HRT examination were analysed. One hundred and nine patients had an HRT classified as normal on the MRA and had a good quality image. Fifteen of those 109 patients (13,7%) were classified as glaucomatous on the basis of an abnormal ODP with matching visual field defect. Seven patients were classified as glaucoma suspect. Conclusion: The rate of false negative results is too high to use the HRT II alone for glaucoma screening.
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • imaging/image analysis: clinical • optic disc