Abstract
Abstract: :
Purpose: To compare polarimetric parameters and study the possible differences in the pattern of RNFL damage between HTG and NTG with scanning laser polarimeter with customized corneal compensation (GDx–VCC) Method: Fifty–two consecutive patients with glaucoma were prospectively recruited for this study. For each patient, only one eye was randomly chosen if both eyes met the inclusion criteria. There were 24 patients with HTG (mean age: 59.9±2.0, Humphrey mean deviation: –6.7±0.98dB) and 28 age–matched patients with NTG (mean age: 60.±1.9, Humphrey mean deviation: –5.9±0.68dB). Each patient underwent GDx–VCC. Findings were compared with t–test between 2 groups Results: No significant differences were found between HTG and NTG eyes for GDx–VCC parameters including symmetry, superior ratio, inferior ratio, superior nasal ratio, ellipse average, superior average, and inferior average. However, NFI (neural–network–based summary parameter) only showed a significant difference between the two groups. Conclusion: No differences in the pattern of RNFL damage were apparent between HTG and NTG based on available topographic parameters as measured by GDx–VCC in our series of glaucomatous eyes in the early to moderate stage. Novel method or parameter which reflects focal or early RNFL change as seen in the NTG may result in better recognition of different pattern of RNFL damage and elucidate the possible difference in pathogenesis between NTG and HTG.
Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound)