Abstract
Abstract: :
Purpose: The Pediatric Vision Screener (PVS) was designed to detect amblyopia risk factors in preschool children by detecting alignment and focus from a distance of 40 cm. In a previous study, the PVS effectively detected strabismus in adults with high sensitivity and specificity.1 In this study the clinical performance of the PVS was assessed in children. Methods: A comprehensive eye examination was performed. PVS scans were obtained (≥3 measurements, 1 reading/0.5s) while subjects fixated on the blinking PVS target. PVS measurements included "binocularity" (alignment) and "C/A" (focus). Results: The study group included 62 children (30 controls, 32 patients) aged 1.1–18 yr (median 5.5 yr). Race was Caucasian in 72%; eye color was brown in 49%. Patients were grouped as "constant strabismus" (range 1Δ–80Δ, n=23), "variable strabismus" (intermittent fusion, range 6Δ–42Δ, n=7), or "anisometropia" (>2D interocular difference, n=2). Binocularity scores were ≤16% in constant strabismus and ≤40% in variable strabismus. In the control group, 29/30 had binocularity >66%. (The youngest control, aged 13 months, measured 10% binocularity.) Conclusions: The PVS showed very high sensitivity and specificity for detection of amblyopia risk factors. Larger scale testing will determine whether the PVS will effectively identify preschool children at risk for amblyopia.
Keywords: screening for ambylopia and strabismus • nerve fiber layer • refraction