May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
A Review Of Clinical Signs And Symptoms In Primary Sjogren's Syndrome And Severe Dry Eye
Author Affiliations & Notes
  • B. Caffery
    Sjogren's Syndrome Clinic, Toronto Western Hospital, Toronto, ON, Canada
  • A. Slomovic
    Sjogren's Syndrome Clinic, Toronto Western Hospital, Toronto, ON, Canada
  • A. Bookman
    Sjogren's Syndrome Clinic, Toronto Western Hospital, Toronto, ON, Canada
  • J. McComb
    Sjogren's Syndrome Clinic, Toronto Western Hospital, Toronto, ON, Canada
  • J. Rutka
    Sjogren's Syndrome Clinic, Toronto Western Hospital, Toronto, ON, Canada
  • X.C. Tong
    Sjogren's Syndrome Clinic, Toronto Western Hospital, Toronto, ON, Canada
  • B. Sabharwal
    Sjogren's Syndrome Clinic, Toronto Western Hospital, Toronto, ON, Canada
  • Footnotes
    Commercial Relationships  B. Caffery, None; A. Slomovic, None; A. Bookman, None; J. McComb, None; J. Rutka, None; X.C. Tong, None; B. Sabharwal, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 3884. doi:
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      B. Caffery, A. Slomovic, A. Bookman, J. McComb, J. Rutka, X.C. Tong, B. Sabharwal; A Review Of Clinical Signs And Symptoms In Primary Sjogren's Syndrome And Severe Dry Eye . Invest. Ophthalmol. Vis. Sci. 2004;45(13):3884.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To assess the pattern of clinical findings and symptoms in a group of primary Sjogren's Syndrome (PSS) patients and those with severe dry eyes and no autoimmune disease (SICCA). Methods: A chart review of 188 PSS and 90 SICCA patients seen in the Toronto Western Hospital SS Clinic over the past 12 years was conducted. Six diagnostic criteria for PSS and patient ranking of severity were recorded and analyzed using SPSS. Results: Within the PSS and SICCA groups there were significant correlations between Schirmer values and rose bengal staining (p=0.028, p<0.001), and symptoms and rose bengal staining (p=0.024, p=0.008). Overall, PSS patients had greater rose bengal staining scores than the SICCA patients. Conclusions: The relationship between rose bengal staining, Schirmer values and symptoms is similar within each of these two groups. However PSS patients present with greater rose bengal staining.

Keywords: cornea: tears/tear film/dry eye 
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