May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Structural and functional outcomes of ROP
Author Affiliations & Notes
  • F. Molle
    Department of Ophthalmology,
    Catholic University, Rome, Italy
  • D. Lepore
    Department of Ophthalmology,
    Catholic University, Rome, Italy
  • G. D'Amico
    Department of Ophthalmology,
    Catholic University, Rome, Italy
  • M. Bruno
    Department of Ophthalmology,
    Catholic University, Rome, Italy
  • R. De Santis
    Department of Ophthalmology,
    Catholic University, Rome, Italy
  • M.M. Pagliara
    Department of Ophthalmology,
    Catholic University, Rome, Italy
  • F. Gallini
    Nicu,
    Catholic University, Rome, Italy
  • C. Romagnoli
    Nicu,
    Catholic University, Rome, Italy
  • Footnotes
    Commercial Relationships  F. Molle, None; D. Lepore, None; G. D'Amico, None; M. Bruno, None; R. De Santis, None; M.M. Pagliara, None; F. Gallini, None; C. Romagnoli, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 4022. doi:
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      F. Molle, D. Lepore, G. D'Amico, M. Bruno, R. De Santis, M.M. Pagliara, F. Gallini, C. Romagnoli; Structural and functional outcomes of ROP . Invest. Ophthalmol. Vis. Sci. 2004;45(13):4022.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: To evaluate the long term outcome of different ROP stages. Materials and Methods: from Jan ‘98 to Dec ’01 487 inborn preterm children (BW less than 1251gr and/or GA ≤32 weeks) were screened for ROP in the neonatal intensive care unit at the Catholic University Hospital in Rome. The mean BW was 1284,65gr (range 415–2620gr) and the mean GA was 29,55 weeks (range 23–35w). Ten babies died inside the NICU. ROP was diagnosed in 160 infants with a mean BW 911,78 grams (range 440–1530) and mean GA 27,66 (range 23–34w). 14,29% of ROP reached threshold (3,72% of all preterm infants) and were treated with cryo (before ’99) or laser: six of them died during the first year of life. A follow–up program for ROP babies was set based on cycloplegic refraction (using an automated refractometer), fundus, anterior segment and motility exam. Results:we present data from babies with a minimum of 1 year follow–up. Cycloplegic refraction was obtained in 78 babies at 1 years with a mean spherical equivalent of +1,84. and +1,22 at 3 years. Babies with threshold ROP showed a a spherical equivalent of +1,39 (range 3,00 –0.75) while stage 3 babies have a spherical of +1,78 and stage 1 and 2 +1,86 (range +8,00 –7,00). At 3 years follow up more than a half of babies with not treated stage 3 ROP showed a manifest strabismus: 21,74 were exotropic and 34,38 esotropic. Conclusions: surgical ablation of avascular retina seems to deeply modify the natural outcome of stage 3 ROP. Data from a long term follow up is necessary to improve the visual development of preterm infants.

Keywords: retinopathy of prematurity • clinical (human) or epidemiologic studies: outcomes/complications 
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