May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Computerized Reading of Digital Wide–Field Retinal Images of Prematures at Risk for Retinopathy of Prematurity (ROP)
Author Affiliations & Notes
  • B. Lorenz
    Dept of Paediat Ophthalmology, Strabismology, and Ophthalmogenetics, University of Regensburg, Klinikum, Regensburg, Germany
  • S. Augustin
    Bavarian Research Center for Knowdlege–based Systems (ForWiss), University of Passau, Passau, Germany
  • M. Donaubauer
    Bavarian Research Center for Knowdlege–based Systems (ForWiss), University of Passau, Passau, Germany
  • G. Pisinger
    Bavarian Research Center for Knowdlege–based Systems (ForWiss), University of Passau, Passau, Germany
  • H. Elflein
    Dept of Paediat Ophthalmology, Strabismology, and Ophthalmogenetics, University of Regensburg, Klinikum, Regensburg, Germany
  • M.N. Preising
    Dept of Paediat Ophthalmology, Strabismology, and Ophthalmogenetics, University of Regensburg, Klinikum, Regensburg, Germany
  • A.L. Ells
    Dept. of Ophthalmology, Alberta Children’s Hospital, Calgary, AB, Canada
  • Footnotes
    Commercial Relationships  B. Lorenz, None; S. Augustin, None; M. Donaubauer, None; G. Pisinger, None; H. Elflein, None; M.N. Preising, None; A.L. Ells, None.
  • Footnotes
    Support  Bayerische Landesstiftung, Bayerische Sparkassenstiftung, DFG LO 457/4–1,2
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 4030. doi:
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      B. Lorenz, S. Augustin, M. Donaubauer, G. Pisinger, H. Elflein, M.N. Preising, A.L. Ells; Computerized Reading of Digital Wide–Field Retinal Images of Prematures at Risk for Retinopathy of Prematurity (ROP) . Invest. Ophthalmol. Vis. Sci. 2004;45(13):4030.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Abstract: : Purpose: Telemedicine screening for Retinopathy of Prematurity (ROP) using digital imaging technology has been under investigation for 5 years. Key for a reliable program is traceable reading of analyzable images. We therefore have developed and evaluated a customized software for reading the images onsite or in a remote setting. Methods: A software has been developed to allow standardized evaluation of digital wide–field images from prematures at risk for ROP and archiving of the pediatric data, the digital images and the ophthalmological evaluation. It includes a dynamic grid positioning feature that can be superimposed to all images from the same eye and a semi–automatic quantification of the ROP stages per zone and clock hour. To test the system, RetCam–120 digital wide–field images from100 consecutive ROP screening examinations on 25 infants were analyzed with the software. The images had been obtained to compare binocular indirect ophthalmoscopy with digital imaging (Ells et al., Ophthalmology 2003). Image sets devoid of any pediatric data were grouped by visit and then analyzed by consecutive visit number in order to eliminate bias in evaluation. Results: The digital software allows traceable classification of the ROP stages per zone and clock hour. The results from individual images can be easily evaluated statistically also for a larger cohort. Grid placement is complicated by the absence of a clear fovea in extreme prematures and by the difficulty to image the nasal ora serrata. Image analysis (both eyes) and creation of a detailed report including recommendations as to follow–up or referral takes about 15 minutes. Conclusions: New software for analysis of digital ROP images allows standardized and traceable ROP remote (and onsite) evaluation. The requested time appears reasonable.

Keywords: retinopathy of prematurity • clinical (human) or epidemiologic studies: systems/equipment/techniques • clinical (human) or epidemiologic studies: risk factor assessment 
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