May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Subthreshold micropulse diode laser treatment in diabetic macular edema. A comparative pilot study.
M.L. Laursen; F. Moeller; B. Sander; A.K. Sjolie
Author Affiliations & Notes
  • M.L. Laursen
    Dept. of Ophthalmology, Odense University Hospital, Odense, Denmark
  • F. Moeller
    Dept. of Ophthalmology, Odense University Hospital, Odense, Denmark
  • B. Sander
    Dept. of Ophthalmology, Herlev Hospital, University of Copenhagen, Herlev, Denmark
  • A.K. Sjolie
    Dept. of Ophthalmology, Odense University Hospital, Odense, Denmark
  • Footnotes
    Commercial Relationships  M.L. Laursen, None; F. Moeller, None; B. Sander, None; A.K. Sjolie, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 4076. doi:
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      M.L. Laursen, F. Moeller, B. Sander, A.K. Sjolie; Subthreshold micropulse diode laser treatment in diabetic macular edema. A comparative pilot study. . Invest. Ophthalmol. Vis. Sci. 2004;45(13):4076.

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Abstract

Abstract: : Purpose: to compare the effectiveness of subthreshold micropulse diode laser (810nm) and conventional argon laser (514 nm) photocoagulation for the treatment of clinically significant macular edema in diabetic patients. Methods: 23 eyes of 16 patients were randomized to either treatment. Follow–up was conducted for a minimum of 5 months. Changes in visual acuity and macular edema measured by optical coherence tomography were examined. Results: Visual acuity remained stable in all treatment groups throughout the observation period. Changes in retinal thickness were small both foveally and perifoveally. In patients with focal macular edema a significant reduction in retinal thickness (9% ∼ –26µm, p=0.02) was seen foveally 3 months after diode laser photocoagulation. Conclusions: Subthreshold micropulse diode laser and conventional argon laser treatment showed an equally good effect on visual acuity. Subthreshold micropulse diode laser showed a stabilizing or even improving effect on macular edema. The combination of micropulse diode laser followed by supplementary argon laser may be particularly favourable in treatment of diabetic macular edema.

Keywords: diabetic retinopathy • laser • clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials 
© 2004, The Association for Research in Vision and Ophthalmology, Inc., all rights reserved. Permission to republish any abstract or part of an abstract in any form must be obtained in writing from the ARVO Office prior to publication.
Copyright © 2015 Association for Research in Vision and Ophthalmology.
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