May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Subthreshold micropulse diode laser treatment in diabetic macular edema. A comparative pilot study.
Author Affiliations & Notes
  • M.L. Laursen
    Dept. of Ophthalmology, Odense University Hospital, Odense, Denmark
  • F. Moeller
    Dept. of Ophthalmology, Odense University Hospital, Odense, Denmark
  • B. Sander
    Dept. of Ophthalmology, Herlev Hospital, University of Copenhagen, Herlev, Denmark
  • A.K. Sjolie
    Dept. of Ophthalmology, Odense University Hospital, Odense, Denmark
  • Footnotes
    Commercial Relationships  M.L. Laursen, None; F. Moeller, None; B. Sander, None; A.K. Sjolie, None.
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 4076. doi:
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      M.L. Laursen, F. Moeller, B. Sander, A.K. Sjolie; Subthreshold micropulse diode laser treatment in diabetic macular edema. A comparative pilot study. . Invest. Ophthalmol. Vis. Sci. 2004;45(13):4076.

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Abstract

Abstract: : Purpose: to compare the effectiveness of subthreshold micropulse diode laser (810nm) and conventional argon laser (514 nm) photocoagulation for the treatment of clinically significant macular edema in diabetic patients. Methods: 23 eyes of 16 patients were randomized to either treatment. Follow–up was conducted for a minimum of 5 months. Changes in visual acuity and macular edema measured by optical coherence tomography were examined. Results: Visual acuity remained stable in all treatment groups throughout the observation period. Changes in retinal thickness were small both foveally and perifoveally. In patients with focal macular edema a significant reduction in retinal thickness (9% ∼ –26µm, p=0.02) was seen foveally 3 months after diode laser photocoagulation. Conclusions: Subthreshold micropulse diode laser and conventional argon laser treatment showed an equally good effect on visual acuity. Subthreshold micropulse diode laser showed a stabilizing or even improving effect on macular edema. The combination of micropulse diode laser followed by supplementary argon laser may be particularly favourable in treatment of diabetic macular edema.

Keywords: diabetic retinopathy • laser • clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials 
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