Abstract
Abstract: :
Purpose:The aim of this study was to determine the effect of BRVO on WF– mfERG P1 amplitudes and P1 implicit times in the affected quadrant and secondly, to compare the WF–mfERG first order parameters between the affected and unaffected quadrants in the affected and fellow eye. Methods:WF–mfERG responses were recorded from both eyes of patients diagnosed with BRVO using a custom–built system. The WF–mfERG responses within each quadrant were grouped and averaged. The average response in the affected quadrant was compared to the average response in the opposite quadrant in the affected eye and the symmetrical quadrant in the contra–lateral eye. Results:Thirty–one patients were included, 14 male and 17 female aged 42–77 (mean 65.8 years). There was a significant difference (p<0.05) between both first order responses from the affected quadrant compared to the opposite quadrant in the affected eye. There was also a significant difference (P<0.05) between the first order response from the affected quadrant and the symmetrical quadrant in the contra–lateral eye. Conclusions:We present a sensitive, objective technique that may be of value in the follow–up of patients with BRVO. WF–mfERG may also become a useful research tool for the objective evaluation of retinal function following new surgical interventions, currently under evaluation for the treatment of BRVO.
Keywords: electroretinography: clinical • retina: distal (photoreceptors, horizontal cells, bipolar cells) • retinal neovascularization