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A. Aoyama, Y. Tamada, A. Sawada, T. Yamamoto; Favorable effect of trabeculectomy on visual field defect progression in eyes with normal–tension glaucoma. . Invest. Ophthalmol. Vis. Sci. 2004;45(13):4453.
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© ARVO (1962-2015); The Authors (2016-present)
Purpose: To investigate whether intraocular pressure (IOP) reduction has a favorable effect on visual field progression in eyes with normal–tension glaucoma (NTG).Methods: We reviewed the surgical records of trabeculecutomy with the intraoperative use of adjunctive mitomycin C (MMC), which had been undergone between 1990 and 1998 in our glaucoma service (158 eyes of 111 cases). Thirty–eight eyes of 38 patients with NTG were selected based on the following criteria : the postoperative follow–up period more than 5 years, preoperative mean deviation (MD) better than –25 dB, best–corrected visual acuity > 20/30, and no postoperative complications which may affect visual field progression. The deterioration of glaucomatous visual field after filtering surgery was determined based on the Statpac 2 linear regression analysis. We set the cut–off for postoperative IOP to be 12 mmHg, and evaluated the relationship between postoperative average pressure and glaucomatous visual field progression.Results: The preoperative IOP was 14.9 ± 1.8 mmHg (mean ± SD, range: 11.7∼18.3), which reduced to 9.3 ± 2.6 mmHg (range: 4.4∼16.4) postoperatively. The preoperative MD was –12.72 ± 5.52 dB. In the group, in which postoperative average IOP below 12 mmHg, 35.5% ( 11 / 31 ) of patients showed deterioration of visual field. Whereas in the >12 mmHg group, 100% ( 7 / 7 ) of patients showed progression.Conclusions:The filtering surgery in NTG may effective in slowing further deterioration o the visual field.CR: None
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