May 2004
Volume 45, Issue 13
Free
ARVO Annual Meeting Abstract  |   May 2004
Clinical Characteristics of Latinos with Open–Angle Glaucoma and Ocular Hypertension
Author Affiliations & Notes
  • F.–Y. Pena
    Keck School of Medicine, Univ. of Southern California, Los Angeles, CA
  • M.Y. Lai
    Keck School of Medicine, Univ. of Southern California, Los Angeles, CA
  • B.A. Francis
    Keck School of Medicine, Univ. of Southern California, Los Angeles, CA
  • B.B. Nguyen
    Keck School of Medicine, Univ. of Southern California, Los Angeles, CA
  • J. Deneen
    Keck School of Medicine, Univ. of Southern California, Los Angeles, CA
  • M.R. Wilson
    Texas Tech University Health Sciences Center, Lubbock, TX
  • S.P. Azen
    Keck School of Medicine, Univ. of Southern California, Los Angeles, CA
  • R. Varma
    Keck School of Medicine, Univ. of Southern California, Los Angeles, CA
  • Los Angeles Latino Eye Study Group
    Keck School of Medicine, Univ. of Southern California, Los Angeles, CA
  • Footnotes
    Commercial Relationships  F. Pena, None; M.Y. Lai, None; B.A. Francis, None; B.B. Nguyen, None; J. Deneen, None; M.R. Wilson, None; S.P. Azen, None; R. Varma, None.
  • Footnotes
    Support  NEI EY 11753, RPB
Investigative Ophthalmology & Visual Science May 2004, Vol.45, 4486. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      F.–Y. Pena, M.Y. Lai, B.A. Francis, B.B. Nguyen, J. Deneen, M.R. Wilson, S.P. Azen, R. Varma, Los Angeles Latino Eye Study Group; Clinical Characteristics of Latinos with Open–Angle Glaucoma and Ocular Hypertension . Invest. Ophthalmol. Vis. Sci. 2004;45(13):4486.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Abstract: : Purpose:To characterize the demographic and clinical features of open–angle glaucoma (OAG) and ocular hypertension (OHT) in a population–based sample of Latinos. Methods:The Los Angeles Latino Eye Study is a population–based study of Latinos (primarily Mexican–Americans) aged 40 years and older. Participants underwent a complete ophthalmic examination including measurement of intraocular pressure (IOP), visual field testing (Humphrey C24 SITA standard and/or full threshold C 24–2) and simultaneous stereoscopic optic disc photography. OAG was defined as the presence of an open angle, glaucomatous visual field abnormality and evidence of glaucomatous optic nerve damage. IOP was not considered when defining OAG. OHT was defined as intraocular pressure > 21 mmHg, and the absence of optic nerve damage or an abnormal visual field test. Frequency distributions, chi–square procedures and analysis of variance were used to compare differences in demographic and clinical characteristics between Latinos with OAG and OHT. Results:OAG was present in 293 subjects with mean age 65.4 years (SD ±11.7), mean IOP 17.3 (SD ±5.4) and mean central corneal thickness (CCT) 545 µm (SD ±38). The average mean defect was –9.6dB (SD ±9.0) and the average pattern standard deviation was 5.7dB (SD ±3.5). The most common visual field defects were arcuate scotomas (35%), nasal steps (8%) paracentral scotomas (3%) and altitudinal defects (3%). In Latinos with OAG, the mean horizontal and vertical cup–to–disc ratio on average were 0.7 (SD ±0.13) and 0.7 (SD ±0.11) respectively. OHT was noted in 218 participants with mean age 59.6 years (SD ±11.4) mean IOP 22.9 (SD ±8.1) and mean CCT 568 µm (SD ±42). In participants with OHT the mean horizontal and vertical cup–disc ratio was 0.3 (SD ±0.14). Latinos with OAG were siginificantly older, had lower IOPs, larger cup–disc ratios and thinner CCTs compared to those with OHT (p for all characteristics <0.0001). Conclusions:These data from a population–based sample of Latinos highlight the differences between persons with OHT and OAG.

Keywords: clinical (human) or epidemiologic studies: prevalence/incidence • clinical (human) or epidemiologic studies: natural history 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×